[[File:SystemsBiologyTrendsInMostCitedResearch.PNG|alt=Shows trends in systems biology research. From 1992 to 2013 Database development articles increased. Articles about algorithms have fluctuated but remained fairly steady. Network properties articles and software development articles have remained low but experienced an increased about halfway through the time period 1992-2013. The articles on Metabolic flux analysis decreased from 1992 to 2013. In 1992 algorithms, equations, modeling and simulation articles were most cited. In 2012 the most cited were database development articles.|thumb|不同时间维度生物学论文中被引用频率前30的文章里各个主题的占比,显示了系统生物学研究的趋势。<ref>{{Cite journal|last1=Zou|first1=Yawen|last2=Laubichler|first2=Manfred D.|date=2018-07-25|title=From systems to biology: A computational analysis of the research articles on systems biology from 1992 to 2013|journal=PLOS ONE|language=en|volume=13|issue=7|pages=e0200929|doi=10.1371/journal.pone.0200929|issn=1932-6203|pmc=6059489|pmid=30044828|bibcode=2018PLoSO..1300929Z}}</ref>]]
不同时间维度生物学论文中被引用频率前30的文章里各个主题的占比,显示了系统生物学研究的趋势。<ref>{{Cite journal|last=Zou|first=Yawen|last2=Laubichler|first2=Manfred D.|date=2018-07-25|title=From systems to biology: A computational analysis of the research articles on systems biology from 1992 to 2013|journal=PLOS One|language=en|volume=13|issue=7|pages=e0200929|doi=10.1371/journal.pone.0200929|issn=1932-6203|pmc=6059489|pmid=30044828|bibcode=2018PLoSO..1300929Z}}</ref>