The axes denote cell counts for three types of cells: progenitor (<math>z</math>), osteoblast (<math>y</math>), and chondrocyte (<math>x</math>). Pro-osteoblast stimulus promotes P→O transition.<ref name=CME>{{cite journal | last1 = Kryven| first1 = I.| last2 = Röblitz| first2 = S.| last3 = Schütte| first3 = Ch.| year =2015| title = Solution of the chemical master equation by radial basis functions approximation with interface tracking| journal = BMC Systems Biology | volume = 9| issue = 1| pages = 67| doi = 10.1186/s12918-015-0210-y| pmid = 26449665| pmc= 4599742}} {{open access}}</ref>]] | The axes denote cell counts for three types of cells: progenitor (<math>z</math>), osteoblast (<math>y</math>), and chondrocyte (<math>x</math>). Pro-osteoblast stimulus promotes P→O transition.<ref name=CME>{{cite journal | last1 = Kryven| first1 = I.| last2 = Röblitz| first2 = S.| last3 = Schütte| first3 = Ch.| year =2015| title = Solution of the chemical master equation by radial basis functions approximation with interface tracking| journal = BMC Systems Biology | volume = 9| issue = 1| pages = 67| doi = 10.1186/s12918-015-0210-y| pmid = 26449665| pmc= 4599742}} {{open access}}</ref>]] |