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在进化生物学中,自然发生,或通俗地称为生命起源(OoL),<ref>{{cite book| last1 = Oparin| first1 = Aleksandr Ivanovich|translator1-last = Morgulis| translator1-first = Sergius| year = 1938| title = The Origin of Life| url = https://books.google.com/books?id=Jv8psJCtI0gC| series = Phoenix Edition Series| edition = 2| location = Mineola, New York| publisher = Courier Corporation| publication-date = 2003| isbn = 978-0486495224| access-date = 2018-06-16}}</ref><ref name=Pereto /><ref name="AST-20151218">Compare: {{cite journal |author= Scharf, Caleb |title= A Strategy for Origins of Life Research |date= 18 December 2015 |journal= Astrobiology|volume= 15 |issue= 12 |pages= 1031–1042 |doi= 10.1089/ast.2015.1113 |display-authors= etal |pmid= 26684503 |pmc= 4683543|bibcode= 2015AsBio..15.1031S | quote = What do we mean by the origins of life (OoL)? [...] Since the early 20th century the phrase OoL has been used to refer to the events that occurred during the transition from non-living to living systems on Earth, i.e., the origin of terrestrial biology (Oparin, 1924; Haldane, 1929). The term has largely replaced earlier concepts such as abiogenesis (Kamminga, 1980; Fry, 2000).}}</ref>是生命从非生命物质(如简单的有机化合物)中产生的自然过程。 <ref name="Oparin1953"/><ref name=Pereto>{{cite journal|last= Peretó |first= Juli |year= 2005 |title= Controversies on the origin of life |url= http://www.im.microbios.org/0801/0801023.pdf |journal= International Microbiology|volume= 8 |issue= 1 |pages= 23–31 |pmid= 15906258 |accessdate= 2015-06-01 |url-status= dead |archiveurl= https://web.archive.org/web/20150824074726/http://www.im.microbios.org/0801/0801023.pdf |archivedate= 24 August 2015 |quote = Ever since the historical contributions by Aleksandr I. Oparin, in the 1920s, the intellectual challenge of the origin of life enigma has unfolded based on the assumption that life originated on Earth through physicochemical processes that can be supposed, comprehended, and simulated; that is, there were neither miracles nor spontaneous generations.}}</ref><ref>{{cite journal |last1= Warmflash |first1= David |last2= Warmflash |first2= Benjamin |date= November 2005 |title= Did Life Come from Another World? |journal= Scientific American |volume= 293 |issue= 5 |pages= 64–71 |doi= 10.1038/scientificamerican1105-64|pmid= 16318028 |bibcode= 2005SciAm.293e..64W | quote = According to the conventional hypothesis, the earliest living cells emerged as a result of chemical evolution on our planet billions of years ago in a process called abiogenesis.}}</ref><ref>Yarus, Michael (2010). Life from an RNA World: The Ancestor Within. Cambridge, MA: Harvard University Press. ISBN 978-0-674-05075-4. LCCN 2009044011.</ref>虽然这一过程的细节仍未可知,但主流的科学假说认为,从非生命实体到生命实体的转变不是一个单一的事件,而是一个复杂度逐渐增加的进化过程,其中包括分子的自复制、自组装、自催化和细胞膜的出现。<ref>{{cite journal|url=http://www.biocommunication.at/pdf/publications/biosystems_2016.pdf |title=Crucial steps to life: From chemical reactions to code using agents|journal=Biosystems|volume=140|pages=49–57|doi=10.1016/j.biosystems.2015.12.007|pmid=26723230|year=2016|last1=Witzany|first1=Guenther}}</ref><ref name="AB-20141208">{{cite web |last= Howell |first= Elizabeth |title= How Did Life Become Complex, And Could It Happen Beyond Earth? |url= https://www.astrobio.net/origin-and-evolution-of-life/life-become-complex-happen-beyond-earth/ |date= 8 December 2014 |work= Astrobiology Magazine|accessdate= 14 February 2018 }}</ref><ref name="EA-20150420">{{Cite book |last= Tirard |first= Stephane |title= Abiogenesis – Definition|date= 20 April 2015 |doi= 10.1007/978-3-642-27833-4_2-4 |journal= Encyclopedia of Astrobiology|pages= 1 | quote = Thomas Huxley (1825–1895) used the term abiogenesis in an important text published in 1870. He strictly made the difference between spontaneous generation, which he did not accept, and the possibility of the evolution of matter from inert to living, without any influence of life. [...] Since the end of the nineteenth century, evolutive abiogenesis means increasing complexity and evolution of matter from inert to living state in the abiotic context of evolution of primitive Earth. |isbn= 978-3-642-27833-4 }}</ref>虽然自然发生的发生在科学家中是没有争议的,但其可能的机制我们却不甚了解。关于自然发生如何发生,有几种原理和假说。<ref>{{Cite book |title=Rethinking evolution: the revolution that's hiding in plain sight  |last=Levinson |first=Gene |publisher=World Scientific |year=2020 |isbn=978-1786347268 |url=https://rethinkingevolution.com/}}</ref>
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在进化生物学中,自然发生,或通俗地称为生命起源(Abiogenesis)(OoL),<ref>{{cite book| last1 = Oparin| first1 = Aleksandr Ivanovich|translator1-last = Morgulis| translator1-first = Sergius| year = 1938| title = The Origin of Life| url = https://books.google.com/books?id=Jv8psJCtI0gC| series = Phoenix Edition Series| edition = 2| location = Mineola, New York| publisher = Courier Corporation| publication-date = 2003| isbn = 978-0486495224| access-date = 2018-06-16}}</ref><ref name=Pereto /><ref name="AST-20151218">Compare: {{cite journal |author= Scharf, Caleb |title= A Strategy for Origins of Life Research |date= 18 December 2015 |journal= Astrobiology|volume= 15 |issue= 12 |pages= 1031–1042 |doi= 10.1089/ast.2015.1113 |display-authors= etal |pmid= 26684503 |pmc= 4683543|bibcode= 2015AsBio..15.1031S | quote = What do we mean by the origins of life (OoL)? [...] Since the early 20th century the phrase OoL has been used to refer to the events that occurred during the transition from non-living to living systems on Earth, i.e., the origin of terrestrial biology (Oparin, 1924; Haldane, 1929). The term has largely replaced earlier concepts such as abiogenesis (Kamminga, 1980; Fry, 2000).}}</ref>是生命从非生命物质(如简单的有机化合物)中产生的自然过程。 <ref name="Oparin1953"/><ref name=Pereto>{{cite journal|last= Peretó |first= Juli |year= 2005 |title= Controversies on the origin of life |url= http://www.im.microbios.org/0801/0801023.pdf |journal= International Microbiology|volume= 8 |issue= 1 |pages= 23–31 |pmid= 15906258 |accessdate= 2015-06-01 |url-status= dead |archiveurl= https://web.archive.org/web/20150824074726/http://www.im.microbios.org/0801/0801023.pdf |archivedate= 24 August 2015 |quote = Ever since the historical contributions by Aleksandr I. Oparin, in the 1920s, the intellectual challenge of the origin of life enigma has unfolded based on the assumption that life originated on Earth through physicochemical processes that can be supposed, comprehended, and simulated; that is, there were neither miracles nor spontaneous generations.}}</ref><ref>{{cite journal |last1= Warmflash |first1= David |last2= Warmflash |first2= Benjamin |date= November 2005 |title= Did Life Come from Another World? |journal= Scientific American |volume= 293 |issue= 5 |pages= 64–71 |doi= 10.1038/scientificamerican1105-64|pmid= 16318028 |bibcode= 2005SciAm.293e..64W | quote = According to the conventional hypothesis, the earliest living cells emerged as a result of chemical evolution on our planet billions of years ago in a process called abiogenesis.}}</ref><ref>Yarus, Michael (2010). Life from an RNA World: The Ancestor Within. Cambridge, MA: Harvard University Press. ISBN 978-0-674-05075-4. LCCN 2009044011.</ref>虽然这一过程的细节仍未可知,但主流的科学假说认为,从非生命实体到生命实体的转变不是一个单一的事件,而是一个复杂度逐渐增加的进化过程,其中包括分子的自复制、自组装、自催化和细胞膜的出现。<ref>{{cite journal|url=http://www.biocommunication.at/pdf/publications/biosystems_2016.pdf |title=Crucial steps to life: From chemical reactions to code using agents|journal=Biosystems|volume=140|pages=49–57|doi=10.1016/j.biosystems.2015.12.007|pmid=26723230|year=2016|last1=Witzany|first1=Guenther}}</ref><ref name="AB-20141208">{{cite web |last= Howell |first= Elizabeth |title= How Did Life Become Complex, And Could It Happen Beyond Earth? |url= https://www.astrobio.net/origin-and-evolution-of-life/life-become-complex-happen-beyond-earth/ |date= 8 December 2014 |work= Astrobiology Magazine|accessdate= 14 February 2018 }}</ref><ref name="EA-20150420">{{Cite book |last= Tirard |first= Stephane |title= Abiogenesis – Definition|date= 20 April 2015 |doi= 10.1007/978-3-642-27833-4_2-4 |journal= Encyclopedia of Astrobiology|pages= 1 | quote = Thomas Huxley (1825–1895) used the term abiogenesis in an important text published in 1870. He strictly made the difference between spontaneous generation, which he did not accept, and the possibility of the evolution of matter from inert to living, without any influence of life. [...] Since the end of the nineteenth century, evolutive abiogenesis means increasing complexity and evolution of matter from inert to living state in the abiotic context of evolution of primitive Earth. |isbn= 978-3-642-27833-4 }}</ref>虽然自然发生的发生在科学家中是没有争议的,但其可能的机制我们却不甚了解。关于自然发生如何发生,有几种原理和假说。<ref>{{Cite book |title=Rethinking evolution: the revolution that's hiding in plain sight  |last=Levinson |first=Gene |publisher=World Scientific |year=2020 |isbn=978-1786347268 |url=https://rethinkingevolution.com/}}</ref>
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====同手性====
 
====同手性====
同手性是指由手性单元组成的某些材料的几何均匀性。手性是指不可重叠的三维形态,它们是彼此的镜像,就像左手和右手一样。生物体使用的分子具有相同的手性("利手性"):几乎没有例外,<ref>Chaichian, Masud; Rojas, Hugo Perez; Tureanu, Anca (2014). "Physics and Life". Basic Concepts in Physics: From the Cosmos to Quarks. Undergraduate Lecture Notes in Physics. Berlin; Heidelberg: Springer Berlin Heidelberg. doi:10.1007/978-3-642-19598-3_12. ISBN 978-3-642-19597-6. LCCN 2013950482. OCLC 900189038.pp353–364}}</ref>氨基酸是左旋的,而核苷酸和糖类是右旋的。手性分子可以合成,但在没有手性源或手性催化剂的情况下,它们是以两种对映体以50/50的混合物(称为外消旋混合物)形成的。已知从外消旋起始原料产生非外消旋混合物的机制包括:非对称物理定律,如弱电相互作用;非对称环境,如圆偏振光、石英晶体或地球自转引起的环境,外消旋合成过程中的统计波动,<ref name="Plasson2007">{{cite journal |last1=Plasson |first1=Raphaël |last2=Kondepudi |first2=Dilip K. |last3=Bersini |first3=Hugues |last4=Commeyras |first4=Auguste |last5=Asakura |first5=Kouichi |display-authors=3 |date=August 2007 |title=Emergence of homochirality in far-from-equilibrium systems: Mechanisms and role in prebiotic chemistry |journal=Chirality |volume=19 |issue=8 |pages=589–600 |doi=10.1002/chir.20440 |pmid=17559107}} "Special Issue: Proceedings from the Eighteenth International Symposium on Chirality (ISCD-18), Busan, Korea, 2006"</ref>以及自发的对称性破缺。<ref name="jafarpour2017">{{cite journal |last1=Jafarpour |first1=Farshid |last2=Biancalani |first2=Tommaso |last3=Goldenfeld |first3=Nigel |year=2017 |title=Noise-induced symmetry breaking far from equilibrium and the emergence of biological homochirality |journal=Physical Review E |volume=95 |issue=3 |pages=032407 |doi=10.1103/PhysRevE.95.032407|pmid=28415353 |bibcode=2017PhRvE..95c2407J |url=http://dspace.mit.edu/bitstream/1721.1/109170/1/PhysRevE.95.032407.pdf }}</ref><ref name="jafarpour2015">{{cite journal |last1=Jafarpour |first1=Farshid |last2=Biancalani |first2=Tommaso |last3=Goldenfeld |first3=Nigel |year=2015 |title=Noise-induced mechanism for biological homochirality of early life self-replicators |journal=Physical Review Letters |volume=115 |issue=15 |pages=158101 |doi=10.1103/PhysRevLett.115.158101|pmid=26550754 |arxiv=1507.00044 |bibcode=2015PhRvL.115o8101J}}</ref><ref name="frank1953">{{cite journal |last1=Frank |first1=F.C. |year=1953 |title=On spontaneous asymmetric synthesis |journal=Biochimica et Biophysica Acta |volume=11 |issue=4 |pages=459–463 |doi=10.1016/0006-3002(53)90082-1|pmid=13105666 }}</ref>
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同手性是指由手性单元组成的某些材料的几何均匀性。手性是指不可重叠的三维形态,它们是彼此的镜像,就像左手和右手一样。生物体使用的分子具有相同的手性("利手性"):几乎没有例外,<ref>Chaichian, Masud; Rojas, Hugo Perez; Tureanu, Anca (2014). "Physics and Life". Basic Concepts in Physics: From the Cosmos to Quarks. Undergraduate Lecture Notes in Physics. Berlin; Heidelberg: Springer Berlin Heidelberg. doi:10.1007/978-3-642-19598-3_12. ISBN 978-3-642-19597-6<nowiki>. LCCN 2013950482. OCLC 900189038.pp353–364}}</nowiki></ref>氨基酸是左旋的,而核苷酸和糖类是右旋的。手性分子可以合成,但在没有手性源或手性催化剂的情况下,它们是以两种对映体以50/50的混合物(称为外消旋混合物)形成的。已知从外消旋起始原料产生非外消旋混合物的机制包括:非对称物理定律,如弱电相互作用;非对称环境,如圆偏振光、石英晶体或地球自转引起的环境,外消旋合成过程中的统计波动,<ref name="Plasson2007">{{cite journal |last1=Plasson |first1=Raphaël |last2=Kondepudi |first2=Dilip K. |last3=Bersini |first3=Hugues |last4=Commeyras |first4=Auguste |last5=Asakura |first5=Kouichi |display-authors=3 |date=August 2007 |title=Emergence of homochirality in far-from-equilibrium systems: Mechanisms and role in prebiotic chemistry |journal=Chirality |volume=19 |issue=8 |pages=589–600 |doi=10.1002/chir.20440 |pmid=17559107}} "Special Issue: Proceedings from the Eighteenth International Symposium on Chirality (ISCD-18), Busan, Korea, 2006"</ref>以及自发的对称性破缺。<ref name="jafarpour2017">{{cite journal |last1=Jafarpour |first1=Farshid |last2=Biancalani |first2=Tommaso |last3=Goldenfeld |first3=Nigel |year=2017 |title=Noise-induced symmetry breaking far from equilibrium and the emergence of biological homochirality |journal=Physical Review E |volume=95 |issue=3 |pages=032407 |doi=10.1103/PhysRevE.95.032407|pmid=28415353 |bibcode=2017PhRvE..95c2407J |url=http://dspace.mit.edu/bitstream/1721.1/109170/1/PhysRevE.95.032407.pdf }}</ref><ref name="jafarpour2015">{{cite journal |last1=Jafarpour |first1=Farshid |last2=Biancalani |first2=Tommaso |last3=Goldenfeld |first3=Nigel |year=2015 |title=Noise-induced mechanism for biological homochirality of early life self-replicators |journal=Physical Review Letters |volume=115 |issue=15 |pages=158101 |doi=10.1103/PhysRevLett.115.158101|pmid=26550754 |arxiv=1507.00044 |bibcode=2015PhRvL.115o8101J}}</ref><ref name="frank1953">{{cite journal |last1=Frank |first1=F.C. |year=1953 |title=On spontaneous asymmetric synthesis |journal=Biochimica et Biophysica Acta |volume=11 |issue=4 |pages=459–463 |doi=10.1016/0006-3002(53)90082-1|pmid=13105666 }}</ref>
     
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