| As a [[paradigm]], systems biology is usually defined in antithesis to the so-called [[reductionist]] paradigm ([[biological organisation]]), although it's fully consistent with the [[scientific method]]. The distinction between the two paradigms is referred to in these quotations: "The [[Reductionism|reductionist]] approach has successfully identified most of the components and many of the interactions but, unfortunately, offers no convincing concepts or methods to understand how system properties emerge ... the pluralism of causes and effects in biological networks is better addressed by observing, through quantitative measures, multiple components simultaneously and by rigorous data integration with mathematical models." (Sauer ''et al.'')<ref name="sauer07" /> "Systems biology ... is about putting together rather than taking apart, integration rather than reduction. It requires that we develop ways of thinking about integration that are as rigorous as our reductionist programmes, but different. ... It means changing our philosophy, in the full sense of the term." ([[Denis Noble]])<ref name="noble06" /> | | As a [[paradigm]], systems biology is usually defined in antithesis to the so-called [[reductionist]] paradigm ([[biological organisation]]), although it's fully consistent with the [[scientific method]]. The distinction between the two paradigms is referred to in these quotations: "The [[Reductionism|reductionist]] approach has successfully identified most of the components and many of the interactions but, unfortunately, offers no convincing concepts or methods to understand how system properties emerge ... the pluralism of causes and effects in biological networks is better addressed by observing, through quantitative measures, multiple components simultaneously and by rigorous data integration with mathematical models." (Sauer ''et al.'')<ref name="sauer07" /> "Systems biology ... is about putting together rather than taking apart, integration rather than reduction. It requires that we develop ways of thinking about integration that are as rigorous as our reductionist programmes, but different. ... It means changing our philosophy, in the full sense of the term." ([[Denis Noble]])<ref name="noble06" /> |