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Network Controllability is concerned about the structural controllability of a network. Controllability describes our ability to guide a dynamical system from any initial state to any desired final state in finite time, with a suitable choice of inputs. This definition agrees well with our intuitive notion of control. The controllability of general directed and weighted complex networks has recently been the subject of intense study by a number of groups in wide variety of networks, worldwide. Recent studies by Sharma et al. on multi-type biological networks (gene- gene, miRNA- gene, Protein-protein interaction networks) identified control targets in phenotypically characterized Osteosarcoma showing important role of genes and proteins responsible for maintaining tumor microenvironment.
Network Controllability is concerned about the structural controllability of a network. Controllability describes our ability to guide a dynamical system from any initial state to any desired final state in finite time, with a suitable choice of inputs. This definition agrees well with our intuitive notion of control. The controllability of general directed and weighted complex networks has recently been the subject of intense study by a number of groups in wide variety of networks, worldwide. Recent studies by Sharma et al. on multi-type biological networks (gene- gene, miRNA- gene, Protein-protein interaction networks) identified control targets in phenotypically characterized Osteosarcoma showing important role of genes and proteins responsible for maintaining tumor microenvironment.
'''<font color="#FF8000">网络可控性 Network Controllability </font>'''研究的是网络的结构可控性。可控性描述了我们在有限时间内，通过合适的输入选择，引导动力系统从任何初始状态到任何期望的最终状态的能力。这个定义与我们直观的控制概念非常吻合。一般有向加权复杂网络的可控性是近年来世界范围内许多研究小组的重点研究课题。夏尔马等人最近的研究，在多种生物学网络(基因-基因、 miRNA-基因、蛋白质-蛋白质相互作用网络)上，确定了骨肉瘤表型特征的控制目标，显示了基因和蛋白质在维持肿瘤微环境中的重要作用。
'''<font color="#FF8000">网络可控性 Network Controllability </font>'''研究的是网络的结构可控性。可控性描述了我们在有限时间内，通过合适的输入选择，引导动力系统从任何初始状态到任何期望的最终状态的能力。这个定义与我们直观的控制概念非常吻合。一般有向加权复杂网络的可控性是近年来世界范围内许多研究小组的重点研究课题。夏尔马等人最近在多种生物学网络(基因-基因、 miRNA-基因、蛋白质-蛋白质相互作用网络)上的研究，确定了骨肉瘤表型特征的控制目标，显示了基因和蛋白质在维持肿瘤微环境中的重要作用。