Life is thought to have emerged in the early RNA world when RNA chains began to express the basic conditions necessary for natural selection to operate as conceived by Darwin: heritability, variation of type, and competition for limited resources. Fitness of an RNA replicator (its per capita rate of increase) would likely be a function of adaptive capacities that were intrinsic (in the sense that they were determined by the nucleotide sequence) and the availability of resources. The three primary adaptive capacities may have been (1) the capacity to replicate with moderate fidelity (giving rise to both heritability and variation of type); (2) the capacity to avoid decay; and (3) the capacity to acquire and process resources. These capacities would have been determined initially by the folded configurations of the RNA replicators (see “Ribozyme”) that, in turn, would be encoded in their individual nucleotide sequences. Competitive success among different replicators would have depended on the relative values of these adaptive capacities. | Life is thought to have emerged in the early RNA world when RNA chains began to express the basic conditions necessary for natural selection to operate as conceived by Darwin: heritability, variation of type, and competition for limited resources. Fitness of an RNA replicator (its per capita rate of increase) would likely be a function of adaptive capacities that were intrinsic (in the sense that they were determined by the nucleotide sequence) and the availability of resources. The three primary adaptive capacities may have been (1) the capacity to replicate with moderate fidelity (giving rise to both heritability and variation of type); (2) the capacity to avoid decay; and (3) the capacity to acquire and process resources. These capacities would have been determined initially by the folded configurations of the RNA replicators (see “Ribozyme”) that, in turn, would be encoded in their individual nucleotide sequences. Competitive success among different replicators would have depended on the relative values of these adaptive capacities. |