更改

XNA可以通过与靶DNA序列杂交，作为定量实时聚合酶链式反应 quantitative real-time polymerase chain reaction（qPCR）的分子钳。<ref name="A novel xenonucleic acid-mediated m">{{cite journal | vauthors = Sun Q, Pastor L, Du J, Powell MJ, Zhang A, Bodmer W, Wu J, Zheng S, Sha MY | display-authors = 6 | title = A novel xenonucleic acid-mediated molecular clamping technology for early colorectal cancer screening | journal = PLOS ONE | volume = 16 | issue = 10 | pages = e0244332 | date = 2021-10-05 | pmid = 34610014 | pmc = 8491914 | doi = 10.1371/journal.pone.0244332 | bibcode = 2021PLoSO..1644332S | doi-access = free }}</ref>在《公共科学图书馆》（PLOS ONE）期刊上发表的一项研究中，一种DNA介导的分子钳技术检测到了癌前结直肠癌 colorectal cancer(CRC)病变和结直肠癌的突变无细胞DNA cell-free DN（cfDNA）。<ref name="A novel xenonucleic acid-mediated m"/>XNA还可以作为检测核酸靶序列的高特异性分子探针。<ref>{{cite journal | vauthors = D'Agata R, Giuffrida MC, Spoto G | title = Peptide Nucleic Acid-Based Biosensors for Cancer Diagnosis | journal = Molecules | volume = 22 | issue = 11 | pages = 1951 | date = November 2017 | pmid = 29137122 | doi = 10.3390/molecules22111951 | pmc = 6150339 | doi-access = free }}</ref>

XNA可以通过与靶DNA序列杂交，作为定量实时聚合酶链式反应 quantitative real-time polymerase chain reaction（qPCR）的分子钳。<ref name="A novel xenonucleic acid-mediated m">{{cite journal | vauthors = Sun Q, Pastor L, Du J, Powell MJ, Zhang A, Bodmer W, Wu J, Zheng S, Sha MY | display-authors = 6 | title = A novel xenonucleic acid-mediated molecular clamping technology for early colorectal cancer screening | journal = PLOS ONE | volume = 16 | issue = 10 | pages = e0244332 | date = 2021-10-05 |doi = 10.1371/journal.pone.0244332 | bibcode = 2021PLoSO..1644332S | doi-access = free }}</ref>在《公共科学图书馆》（PLOS ONE）期刊上发表的一项研究中，一种DNA介导的分子钳技术检测到了癌前结直肠癌 colorectal cancer(CRC)病变和结直肠癌的突变无细胞DNA cell-free DN（cfDNA）。<ref name="A novel xenonucleic acid-mediated m"/>XNA还可以作为检测核酸靶序列的高特异性分子探针。<ref>{{cite journal | vauthors = D'Agata R, Giuffrida MC, Spoto G | title = Peptide Nucleic Acid-Based Biosensors for Cancer Diagnosis | journal = Molecules | volume = 22 | issue = 11 | pages = 1951 | date = November 2017 | pmid = 29137122 | doi = 10.3390/molecules22111951 | pmc = 6150339 | doi-access = free }}</ref>

 

== 参见 ==

== 参见 ==