A study of primary visual cortex found that in awake mice, when compared to animals under anesthesia, the spatial tuning of inhibitory synaptic inputs is much wider, suggesting that in awake animals the E/I balance is profoundly skewed towards inhibition (Haider et al., 2013). | A study of primary visual cortex found that in awake mice, when compared to animals under anesthesia, the spatial tuning of inhibitory synaptic inputs is much wider, suggesting that in awake animals the E/I balance is profoundly skewed towards inhibition (Haider et al., 2013). |