198
个编辑
更改
→生物网络分析
With the recent explosion of publicly available high throughput biological data, the analysis of molecular networks has gained significant interest. The type of analysis in this content are closely related to social network analysis, but often focusing on local patterns in the network. For example, [[network motif]]s are small subgraphs that are over-represented in the network. [[Activity motifs]] are similar over-represented patterns in the attributes of nodes and edges in the network that are over represented given the network structure. The analysis of [[biological network]]s has led to the development of [[network medicine]], which looks at the effect of diseases in the [[interactome]].<ref>{{cite journal | last1 = Barabási | first1 = A. L. | last2 = Gulbahce | first2 = N. | last3 = Loscalzo | first3 = J. | year = 2011 | title = Network medicine: a network-based approach to human disease | journal = Nature Reviews Genetics | volume = 12 | issue = 1| pages = 56–68 | doi=10.1038/nrg2918 | pmid=21164525 | pmc=3140052}}</ref>
With the recent explosion of publicly available high throughput biological data, the analysis of molecular networks has gained significant interest. The type of analysis in this content are closely related to social network analysis, but often focusing on local patterns in the network. For example, [[network motif]]s are small subgraphs that are over-represented in the network. [[Activity motifs]] are similar over-represented patterns in the attributes of nodes and edges in the network that are over represented given the network structure. The analysis of [[biological network]]s has led to the development of [[network medicine]], which looks at the effect of diseases in the [[interactome]].<ref>{{cite journal | last1 = Barabási | first1 = A. L. | last2 = Gulbahce | first2 = N. | last3 = Loscalzo | first3 = J. | year = 2011 | title = Network medicine: a network-based approach to human disease | journal = Nature Reviews Genetics | volume = 12 | issue = 1| pages = 56–68 | doi=10.1038/nrg2918 | pmid=21164525 | pmc=3140052}}</ref>
随着近年来公开的生物学数据的爆炸性增长，分子网络分析引起了人们极大的兴趣。这种分析类型与社会网络分析密切相关，但通常更侧重于网络中的局部模式。例如网络模体（network motifs）是指网络中过表达的小的子图。在给定网络结构的情况下，网络中节点和连边的属性中的活动模体是相似的过表达模式。生物网络的分析促进了网络医学的发展，网络医学主要是从交互中观察疾病的影响。[33]
===链路分析===
===链路分析===