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Molecular structure of DNA

[ DNA 的分子结构]

Self-replication is any behavior of a dynamical system that yields construction of an identical or similar copy of itself. Biological cells, given suitable environments, reproduce by cell division. During cell division, DNA is replicated and can be transmitted to offspring during reproduction. Biological viruses can replicate, but only by commandeering the reproductive machinery of cells through a process of infection. Harmful prion proteins can replicate by converting normal proteins into rogue forms.[1] Computer viruses reproduce using the hardware and software already present on computers. Self-replication in robotics has been an area of research and a subject of interest in science fiction. Any self-replicating mechanism which does not make a perfect copy (mutation) will experience genetic variation and will create variants of itself. These variants will be subject to natural selection, since some will be better at surviving in their current environment than others and will out-breed them.

Self-replication is any behavior of a dynamical system that yields construction of an identical or similar copy of itself. Biological cells, given suitable environments, reproduce by cell division. During cell division, DNA is replicated and can be transmitted to offspring during reproduction. Biological viruses can replicate, but only by commandeering the reproductive machinery of cells through a process of infection. Harmful prion proteins can replicate by converting normal proteins into rogue forms. Computer viruses reproduce using the hardware and software already present on computers. Self-replication in robotics has been an area of research and a subject of interest in science fiction. Any self-replicating mechanism which does not make a perfect copy (mutation) will experience genetic variation and will create variants of itself. These variants will be subject to natural selection, since some will be better at surviving in their current environment than others and will out-breed them.

自我复制是一个动力系统的任何行为,产生一个相同或相似的复制本身的建设。生物细胞,在适当的环境下,通过细胞分裂进行繁殖。在细胞分裂过程中,DNA 被复制,并在生殖过程中传递给后代。生物病毒可以复制,但只能通过感染过程控制细胞的生殖机制。有害的朊病毒蛋白可以通过将正常的蛋白质转化为流氓形式来复制。计算机病毒利用计算机上已有的硬件和软件进行复制。自我复制机器人学一直是一个研究领域,也是科幻小说中的一个兴趣主题。任何不能完美复制的自我复制机制(变异)都会经历遗传变异,并且会产生自身的变异。这些变异将受到自然选择的影响,因为有些变异会比其他变异更好地在当前环境中生存,并将超越他们。



Overview

Overview

概览



Theory

Theory

理论




Early research by John von Neumann[2] established that replicators have several parts:

Early research by John von Neumann established that replicators have several parts:

约翰·冯·诺伊曼的早期研究表明复制因子有几个部分:



  • A coded representation of the replicator


  • A mechanism to copy the coded representation


  • A mechanism for effecting construction within the host environment of the replicator




Exceptions to this pattern may be possible, although none have yet been achieved. For example, scientists have come close to constructing RNA that can be copied in an "environment" that is a solution of RNA monomers and transcriptase. In this case, the body is the genome, and the specialized copy mechanisms are external. The requirement for an outside copy mechanism has not yet been overcome, and such systems are more accurately characterized as "assisted replication" than "self-replication".

Exceptions to this pattern may be possible, although none have yet been achieved. For example, scientists have come close to constructing RNA that can be copied in an "environment" that is a solution of RNA monomers and transcriptase. In this case, the body is the genome, and the specialized copy mechanisms are external. The requirement for an outside copy mechanism has not yet been overcome, and such systems are more accurately characterized as "assisted replication" than "self-replication".

这种模式可能有例外,尽管尚未实现任何例外。例如,科学家们已经接近于在 RNA 单体和转录酶的“环境”中构建[可复制的 https://arstechnica.com/science/2011/04/investigations-into-the-ancient-RNA-world/ RNA ]。在这种情况下,身体就是基因组,专门的复制机制是外部的。对外部复制机制的需求尚未被克服,这种系统更准确地描述为“辅助复制”而不是“自我复制复制”。



However, the simplest possible case is that only a genome exists. Without some specification of the self-reproducing steps, a genome-only system is probably better characterized as something like a crystal.

However, the simplest possible case is that only a genome exists. Without some specification of the self-reproducing steps, a genome-only system is probably better characterized as something like a crystal.

然而,最简单的可能的情况是只有一个基因组存在。如果没有一些自我繁殖步骤的说明,一个只有基因组的系统可能更好地被描述为类似于晶体的东西。



Classes of self-replication

Classes of self-replication

自我复制的类别

Recent research[3] has begun to categorize replicators, often based on the amount of support they require.

Recent research has begun to categorize replicators, often based on the amount of support they require.

最近的研究已经开始对复制因子进行分类,通常基于它们所需要的支持量。



  • Natural replicators have all or most of their design from nonhuman sources. Such systems include natural life forms.


  • Autotrophic replicators can reproduce themselves "in the wild". They mine their own materials. It is conjectured that non-biological autotrophic replicators could be designed by humans, and could easily accept specifications for human products.


  • Self-reproductive systems are conjectured systems which would produce copies of themselves from industrial feedstocks such as metal bar and wire.


  • Self-assembling systems assemble copies of themselves from finished, delivered parts. Simple examples of such systems have been demonstrated at the macro scale.




The design space for machine replicators is very broad. A comprehensive study[4] to date by Robert Freitas and Ralph Merkle has identified 137 design dimensions grouped into a dozen separate categories, including: (1) Replication Control, (2) Replication Information, (3) Replication Substrate, (4) Replicator Structure, (5) Passive Parts, (6) Active Subunits, (7) Replicator Energetics, (8) Replicator Kinematics, (9) Replication Process, (10) Replicator Performance, (11) Product Structure, and (12) Evolvability.

The design space for machine replicators is very broad. A comprehensive study to date by Robert Freitas and Ralph Merkle has identified 137 design dimensions grouped into a dozen separate categories, including: (1) Replication Control, (2) Replication Information, (3) Replication Substrate, (4) Replicator Structure, (5) Passive Parts, (6) Active Subunits, (7) Replicator Energetics, (8) Replicator Kinematics, (9) Replication Process, (10) Replicator Performance, (11) Product Structure, and (12) Evolvability.

机器复制因子的设计空间非常广阔。迄今为止,Robert Freitas 和 Ralph Merkle 的综合研究已经确定了137个设计维度分为十几个独立的类别,包括: (1)复制控制,(2)复制信息,(3)复制基板,(4)复制结构,(5)被动部件,(6)主动子单元,(7)复制能量学,(8)复制机运动学,(9)复制过程,(10)复制机性能,(11)产品结构,和(12)进化性。



A self-replicating computer program

A self-replicating computer program

一种自我复制的电脑程序




In computer science a quine is a self-reproducing computer program that, when executed, outputs its own code. For example, a quine in the Python programming language is:

In computer science a quine is a self-reproducing computer program that, when executed, outputs its own code. For example, a quine in the Python programming language is:

在计算机科学中,quine 是一种自我复制的计算机程序,当执行时,输出自己的代码。例如,Python 的一个 quine 是:



a='a=%r;print(a%%a)';print(a%a)

a='a=%r;print(a%%a)';print(a%a)

代码为‘ a% r; print (a% a)’ ; print (a% a) / code



A more trivial approach is to write a program that will make a copy of any stream of data that it is directed to, and then direct it at itself. In this case the program is treated as both executable code, and as data to be manipulated. This approach is common in most self-replicating systems, including biological life, and is simpler as it does not require the program to contain a complete description of itself.

A more trivial approach is to write a program that will make a copy of any stream of data that it is directed to, and then direct it at itself. In this case the program is treated as both executable code, and as data to be manipulated. This approach is common in most self-replicating systems, including biological life, and is simpler as it does not require the program to contain a complete description of itself.

一种更简单的方法是编写一个程序,该程序将复制它所指向的任何数据流,然后指向它自己。在这种情况下,程序既被当作可执行代码,也被当作要操作的数据。这种方法在包括生物生命在内的大多数自我复制系统中都很常见,而且更简单,因为它不需要程序包含对自身的完整描述。



In many programming languages an empty program is legal, and executes without producing errors or other output. The output is thus the same as the source code, so the program is trivially self-reproducing.

In many programming languages an empty program is legal, and executes without producing errors or other output. The output is thus the same as the source code, so the program is trivially self-reproducing.

在许多编程语言中,空程序是合法的,并且执行时不会产生错误或其他输出。因此,输出是相同的源代码,所以程序是微不足道的自我复制。



Self-replicating tiling

Self-replicating tiling

自我复制瓷砖




In geometry a self-replicating tiling is a tiling pattern in which several congruent tiles may be joined together to form a larger tile that is similar to the original. This is an aspect of the field of study known as tessellation. The "sphinx" hexiamond is the only known self-replicating pentagon.[5] For example, four such concave pentagons can be joined together to make one with twice the dimensions.[6] Solomon W. Golomb coined the term rep-tiles for self-replicating tilings.

In geometry a self-replicating tiling is a tiling pattern in which several congruent tiles may be joined together to form a larger tile that is similar to the original. This is an aspect of the field of study known as tessellation. The "sphinx" hexiamond is the only known self-replicating pentagon. For example, four such concave pentagons can be joined together to make one with twice the dimensions. Solomon W. Golomb coined the term rep-tiles for self-replicating tilings.

在几何学中,一个自我复制的瓷砖是一个瓷砖模式,其中几个相等的瓷砖可以连接在一起,形成一个较大的瓷砖,类似于原来的。这是一个方面的研究领域称为镶嵌。“狮身人面像”赫西阿蒙德是已知唯一能自我复制的五角大楼。例如,四个这样的凹形五边形可以连接在一起,形成一个尺寸是原来两倍的五边形。所罗门·格伦布创造了术语 rep-tiles 来描述自我复制的耕作。



In 2012, Lee Sallows identified rep-tiles as a special instance of a self-tiling tile set or setiset. A setiset of order n is a set of n shapes that can be assembled in n different ways so as to form larger replicas of themselves. Setisets in which every shape is distinct are called 'perfect'. A rep-n rep-tile is just a setiset composed of n identical pieces.

In 2012, Lee Sallows identified rep-tiles as a special instance of a self-tiling tile set or setiset. A setiset of order n is a set of n shapes that can be assembled in n different ways so as to form larger replicas of themselves. Setisets in which every shape is distinct are called 'perfect'. A rep-n rep-tile is just a setiset composed of n identical pieces.

2012年,Lee Sallows 将 rep-tiles 定义为一种特殊的自组合纹样集。一组 n 阶的复制品是一组 n 个形状的复制品,它们可以以 n 种不同的方式组合,以便形成更大的自身复制品。每个形状各不相同的塞提塞称为“完美”。Rep-n rep-tile 只是由 n 个相同部分组成的一个集合。

Four 'sphinx' hexiamonds can be put together to form another sphinx.

sphinx' hexiamonds can be put together to form another sphinx.]]

[人面狮身人面像可以拼凑成另一个人面狮身人面像]

A perfect setiset of order 4

setiset of order 4]]

setiset of order 4]]




Self replicating clay crystals

Self replicating clay crystals

自我复制的粘土晶体

One form of natural self-replication that isn't based on DNA or RNA occurs in clay crystals.[7] Clay consists of a large number of small crystals, and clay is an environment that promotes crystal growth. Crystals consist of a regular lattice of atoms and are able to grow if e.g. placed in a water solution containing the crystal components; automatically arranging atoms at the crystal boundary into the crystalline form. Crystals may have irregularities where the regular atomic structure is broken, and when crystals grow, these irregularities may propagate, creating a form of self-replication of crystal irregularities. Because these irregularities may affect the probability of a crystal breaking apart to form new crystals, crystals with such irregularities could even be considered to undergo evolutionary development.

One form of natural self-replication that isn't based on DNA or RNA occurs in clay crystals. Clay consists of a large number of small crystals, and clay is an environment that promotes crystal growth. Crystals consist of a regular lattice of atoms and are able to grow if e.g. placed in a water solution containing the crystal components; automatically arranging atoms at the crystal boundary into the crystalline form. Crystals may have irregularities where the regular atomic structure is broken, and when crystals grow, these irregularities may propagate, creating a form of self-replication of crystal irregularities. Because these irregularities may affect the probability of a crystal breaking apart to form new crystals, crystals with such irregularities could even be considered to undergo evolutionary development.

一种不是基于 DNA 或 RNA 的天然自我复制存在于粘土晶体中。粘土由大量的小晶体组成,粘土是促进晶体生长的环境。晶体是由规则的原子晶格组成的,如果没有原子晶格,晶体就能够生长。放置在含有晶体成分的水溶液中,自动地将晶体边界上的原子排列成晶体形式。当正常的原子结构被破坏时,晶体可能具有不规则性,当晶体生长时,这些不规则性可能会传播,形成一种晶体不规则性的自我复制。由于这些不规则结构可能会影响晶体分裂形成新晶体的概率,因此这种不规则结构的晶体甚至可以被认为是在进化过程中形成的。



Applications

Applications

申请

It is a long-term goal of some engineering sciences to achieve a clanking replicator, a material device that can self-replicate. The usual reason is to achieve a low cost per item while retaining the utility of a manufactured good. Many authorities say that in the limit, the cost of self-replicating items should approach the cost-per-weight of wood or other biological substances, because self-replication avoids the costs of labor, capital and distribution in conventional manufactured goods.

It is a long-term goal of some engineering sciences to achieve a clanking replicator, a material device that can self-replicate. The usual reason is to achieve a low cost per item while retaining the utility of a manufactured good. Many authorities say that in the limit, the cost of self-replicating items should approach the cost-per-weight of wood or other biological substances, because self-replication avoids the costs of labor, capital and distribution in conventional manufactured goods.

一些工程科学的长期目标是制造出一种可以自我复制的铿锵复制机器。通常的原因是为了在保留生产品的同时降低每件商品的成本。许多权威人士表示,在这个限度内,自我复制产品的成本应该接近木材或其他生物物质的单位重量成本,因为自我复制可以避免传统制成品的劳动力、资本和分销成本。



A fully novel artificial replicator is a reasonable near-term goal.

A fully novel artificial replicator is a reasonable near-term goal.

一个全新的人工复制因子是一个合理的近期目标。

A NASA study recently placed the complexity of a clanking replicator at approximately that of Intel's Pentium 4 CPU.[8] That is, the technology is achievable with a relatively small engineering group in a reasonable commercial time-scale at a reasonable cost.

A NASA study recently placed the complexity of a clanking replicator at approximately that of Intel's Pentium 4 CPU. That is, the technology is achievable with a relatively small engineering group in a reasonable commercial time-scale at a reasonable cost.

美国宇航局最近的一项研究表明,铿锵复制机器的复杂度大约相当于英特尔奔腾4处理器的复杂度。也就是说,这项技术是可以实现的与一个相对较小的工程小组在一个合理的商业时间规模在一个合理的成本。



Given the currently keen interest in biotechnology and the high levels of funding in that field, attempts to exploit the replicative ability of existing cells are timely, and may easily lead to significant insights and advances.

Given the currently keen interest in biotechnology and the high levels of funding in that field, attempts to exploit the replicative ability of existing cells are timely, and may easily lead to significant insights and advances.

鉴于目前对生物技术的浓厚兴趣和这一领域的大量资金,利用现有细胞的复制能力的尝试是及时的,而且很容易产生重大的见解和进展。



A variation of self replication is of practical relevance in compiler construction, where a similar bootstrapping problem occurs as in natural self replication. A compiler (phenotype) can be applied on the compiler's own source code (genotype) producing the compiler itself. During compiler development, a modified (mutated) source is used to create the next generation of the compiler. This process differs from natural self-replication in that the process is directed by an engineer, not by the subject itself.

A variation of self replication is of practical relevance in compiler construction, where a similar bootstrapping problem occurs as in natural self replication. A compiler (phenotype) can be applied on the compiler's own source code (genotype) producing the compiler itself. During compiler development, a modified (mutated) source is used to create the next generation of the compiler. This process differs from natural self-replication in that the process is directed by an engineer, not by the subject itself.

自我复制的一种变体在编译器构造中具有实际意义,在自然自我复制中也会出现类似的自举问题。编译器(表型)可以应用于编译器自身的源代码(基因型) ,从而产生编译器本身。在编译器开发过程中,使用修改(变异)的源代码来创建下一代编译器。这个过程不同于自然自我复制,因为这个过程是由工程师指导的,而不是主体本身。



Mechanical self-replication

Mechanical self-replication

机械自我复制




An activity in the field of robots is the self-replication of machines. Since all robots (at least in modern times) have a fair number of the same features, a self-replicating robot (or possibly a hive of robots) would need to do the following:

An activity in the field of robots is the self-replication of machines. Since all robots (at least in modern times) have a fair number of the same features, a self-replicating robot (or possibly a hive of robots) would need to do the following:

机器人领域的一项活动就是机器的自我复制。由于所有机器人(至少在现代)都有相当数量的相同特性,一个自我复制的机器人(或者可能是一群机器人)需要做以下工作:



  • Obtain construction materials


  • Manufacture new parts including its smallest parts and thinking apparatus


  • Provide a consistent power source


  • Program the new members


  • error correct any mistakes in the offspring




On a nano scale, assemblers might also be designed to self-replicate under their own power. This, in turn, has given rise to the "grey goo" version of Armageddon, as featured in such science fiction novels as Bloom, Prey, and Recursion.

On a nano scale, assemblers might also be designed to self-replicate under their own power. This, in turn, has given rise to the "grey goo" version of Armageddon, as featured in such science fiction novels as Bloom, Prey, and Recursion.

在纳米级别上,组装者也可能被设计成在自身能量下进行自我复制。这反过来又导致了“灰色粘性”版本的世界末日,就像在诸如 Bloom,Prey 和 Recursion 这样的科幻小说中描述的那样。



The Foresight Institute has published guidelines for researchers in mechanical self-replication.[9] The guidelines recommend that researchers use several specific techniques for preventing mechanical replicators from getting out of control, such as using a broadcast architecture.

The Foresight Institute has published guidelines for researchers in mechanical self-replication. The guidelines recommend that researchers use several specific techniques for preventing mechanical replicators from getting out of control, such as using a broadcast architecture.

美国前瞻学会协会已经为机械自我复制的研究人员发布了指导方针。指导方针建议研究人员使用一些特定的技术来防止机械复制器失控,比如使用广播结构。



For a detailed article on mechanical reproduction as it relates to the industrial age see mass production.

For a detailed article on mechanical reproduction as it relates to the industrial age see mass production.

有关与工业时代有关的机械复制的详细文章,请参阅大规模生产。



Fields

Fields

田野

模板:Refimprove section


Research has occurred in the following areas:

Research has occurred in the following areas:

在以下领域进行了研究:



  • Biology studies natural replication and replicators, and their interaction. These can be an important guide to avoid design difficulties in self-replicating machinery.


  • In Chemistry self-replication studies are typically about how a specific set of molecules can act together to replicate each other within the set [10] (often part of Systems chemistry field).


  • Memetics studies ideas and how they propagate in human culture. Memes require only small amounts of material, and therefore have theoretical similarities to viruses and are often described as viral.



  • Space resources: NASA has sponsored a number of design studies to develop self-replicating mechanisms to mine space resources. Most of these designs include computer-controlled machinery that copies itself.



  • In parallel computing, it takes a long time to manually load a new program on every node of a large computer cluster or distributed computing system. Automatically loading new programs using mobile agents can save the system administrator a lot of time and give users their results much quicker, as long as they don't get out of control.




In industry

In industry

在工业界



Space exploration and manufacturing

Space exploration and manufacturing

太空探索和制造业

The goal of self-replication in space systems is to exploit large amounts of matter with a low launch mass. For example, an autotrophic self-replicating machine could cover a moon or planet with solar cells, and beam the power to the Earth using microwaves. Once in place, the same machinery that built itself could also produce raw materials or manufactured objects, including transportation systems to ship the products. Another model of self-replicating machine would copy itself through the galaxy and universe, sending information back.

The goal of self-replication in space systems is to exploit large amounts of matter with a low launch mass. For example, an autotrophic self-replicating machine could cover a moon or planet with solar cells, and beam the power to the Earth using microwaves. Once in place, the same machinery that built itself could also produce raw materials or manufactured objects, including transportation systems to ship the products. Another model of self-replicating machine would copy itself through the galaxy and universe, sending information back.

太空系统中自我复制的目标是利用低发射质量的大量物质。例如,一个自养自我复制机械可以用太阳能电池覆盖月球或行星,并通过微波将能量传送到地球。一旦到位,自己建造的同样的机器也可以生产原材料或制成品,包括运输产品的运输系统。另一个自我复制机械的模型会在银河系和宇宙中复制自己,把信息传回来。



In general, since these systems are autotrophic, they are the most difficult and complex known replicators. They are also thought to be the most hazardous, because they do not require any inputs from human beings in order to reproduce.

In general, since these systems are autotrophic, they are the most difficult and complex known replicators. They are also thought to be the most hazardous, because they do not require any inputs from human beings in order to reproduce.

一般来说,由于这些系统是自养的,他们是最困难和复杂的已知复制因子。它们也被认为是最危险的,因为它们不需要人类的任何投入来繁殖。



A classic theoretical study of replicators in space is the 1980 NASA study of autotrophic clanking replicators, edited by Robert Freitas.[11]

A classic theoretical study of replicators in space is the 1980 NASA study of autotrophic clanking replicators, edited by Robert Freitas.

一个关于太空中复制因子的经典理论研究是1980年 NASA 关于自养叮当复制因子的研究,由 Robert Freitas 编辑。



Much of the design study was concerned with a simple, flexible chemical system for processing lunar regolith, and the differences between the ratio of elements needed by the replicator, and the ratios available in regolith. The limiting element was Chlorine, an essential element to process regolith for Aluminium. Chlorine is very rare in lunar regolith, and a substantially faster rate of reproduction could be assured by importing modest amounts.

Much of the design study was concerned with a simple, flexible chemical system for processing lunar regolith, and the differences between the ratio of elements needed by the replicator, and the ratios available in regolith. The limiting element was Chlorine, an essential element to process regolith for Aluminium. Chlorine is very rare in lunar regolith, and a substantially faster rate of reproduction could be assured by importing modest amounts.

大部分的设计研究都是关于一个简单、灵活的化学系统来处理月球表面的风化层,以及复制因子所需要的元素比率和风化层中可用的比率之间的差异。限制元素是氯,一个必不可少的元素处理风化层的铝。氯在月球的风化层中非常罕见,通过进口适量的氯,可以保证更快的生殖速度。



The reference design specified small computer-controlled electric carts running on rails. Each cart could have a simple hand or a small bull-dozer shovel, forming a basic robot.

The reference design specified small computer-controlled electric carts running on rails. Each cart could have a simple hand or a small bull-dozer shovel, forming a basic robot.

参考设计指定的小型计算机控制的电动车在轨道上运行。每个推车可以有一个简单的手或一个小型推土机铲,形成一个基本的机器人。



Power would be provided by a "canopy" of solar cells supported on pillars. The other machinery could run under the canopy.

Power would be provided by a "canopy" of solar cells supported on pillars. The other machinery could run under the canopy.

电力将由支撑在支柱上的太阳能电池“天篷”提供。其他的机器可以在天篷下面运转。



A "casting robot" would use a robotic arm with a few sculpting tools to make plaster molds. Plaster molds are easy to make, and make precise parts with good surface finishes. The robot would then cast most of the parts either from non-conductive molten rock (basalt) or purified metals. An electric oven melted the materials.

A "casting robot" would use a robotic arm with a few sculpting tools to make plaster molds. Plaster molds are easy to make, and make precise parts with good surface finishes. The robot would then cast most of the parts either from non-conductive molten rock (basalt) or purified metals. An electric oven melted the materials.

一个“铸造机器人”将使用一个机械手臂和一些雕刻工具来制作石膏模具。石膏模具易于制作,而且制作精确的零件表面光洁度好。然后,机器人将用非导电熔岩(玄武岩)或纯净金属铸造大部分零件。电炉熔化了这些材料。



A speculative, more complex "chip factory" was specified to produce the computer and electronic systems, but the designers also said that it might prove practical to ship the chips from Earth as if they were "vitamins".

A speculative, more complex "chip factory" was specified to produce the computer and electronic systems, but the designers also said that it might prove practical to ship the chips from Earth as if they were "vitamins".

他们指定了一个更为复杂的推测性“芯片工厂”来生产计算机和电子系统,但设计师们还表示,将这些芯片像“维生素”一样从地球运输出去,可能会被证明是可行的。



Molecular manufacturing

Molecular manufacturing

分子制造




Nanotechnologists in particular believe that their work will likely fail to reach a state of maturity until human beings design a self-replicating assembler of nanometer dimensions [1].

Nanotechnologists in particular believe that their work will likely fail to reach a state of maturity until human beings design a self-replicating assembler of nanometer dimensions [2].

纳米技术专家尤其相信,在人类设计出一种纳米尺度的自我复制装配器之前,他们的工作很可能无法达到成熟的状态。 Molecularassembler.com/ksrm/4.11.3.htm.



These systems are substantially simpler than autotrophic systems, because they are provided with purified feedstocks and energy. They do not have to reproduce them. This distinction is at the root of some of the controversy about whether molecular manufacturing is possible or not. Many authorities who find it impossible are clearly citing sources for complex autotrophic self-replicating systems. Many of the authorities who find it possible are clearly citing sources for much simpler self-assembling systems, which have been demonstrated. In the meantime, a Lego-built autonomous robot able to follow a pre-set track and assemble an exact copy of itself, starting from four externally provided components, was demonstrated experimentally in 2003 [3].

These systems are substantially simpler than autotrophic systems, because they are provided with purified feedstocks and energy. They do not have to reproduce them. This distinction is at the root of some of the controversy about whether molecular manufacturing is possible or not. Many authorities who find it impossible are clearly citing sources for complex autotrophic self-replicating systems. Many of the authorities who find it possible are clearly citing sources for much simpler self-assembling systems, which have been demonstrated. In the meantime, a Lego-built autonomous robot able to follow a pre-set track and assemble an exact copy of itself, starting from four externally provided components, was demonstrated experimentally in 2003 [4].

这些系统比自养系统简单得多,因为它们提供了纯化的原料和能源。他们不需要复制它们。这种区别是关于分子制造是否可行的一些争论的根源。许多当局认为这是不可能的,他们明确地引用了复杂的自养自我复制系统的资源。许多发现这种可能性的权威人士显然是在引用已经证明的更简单的自组装系统的资料。与此同时,2003年的一项实验展示了一个乐高积木自主机器人,它能够按照预先设定的轨道,从外部提供的4个组件开始,精确地组装出自己的副本。 Molecularassembler.com/ksrm/3.23.4.htm.



Merely exploiting the replicative abilities of existing cells is insufficient, because of limitations in the process of protein biosynthesis (also see the listing for RNA).

Merely exploiting the replicative abilities of existing cells is insufficient, because of limitations in the process of protein biosynthesis (also see the listing for RNA).

仅仅利用现有细胞的复制能力是不够的,因为在蛋白质生物合成过程中存在局限性。

What is required is the rational design of an entirely novel replicator with a much wider range of synthesis capabilities.

What is required is the rational design of an entirely novel replicator with a much wider range of synthesis capabilities.

我们需要的是合理设计一种具有更广泛合成能力的全新复制因子。



In 2011, New York University scientists have developed artificial structures that can self-replicate, a process that has the potential to yield new types of materials. They have demonstrated that it is possible to replicate not just molecules like cellular DNA or RNA, but discrete structures that could in principle assume many different shapes, have many different functional features, and be associated with many different types of chemical species.[12][13]

In 2011, New York University scientists have developed artificial structures that can self-replicate, a process that has the potential to yield new types of materials. They have demonstrated that it is possible to replicate not just molecules like cellular DNA or RNA, but discrete structures that could in principle assume many different shapes, have many different functional features, and be associated with many different types of chemical species.

2011年,纽约大学的科学家们开发出了可以自我复制的人造结构,这一过程有可能产生新型材料。他们已经证明,不仅可以复制像细胞 DNA 或 RNA 这样的分子,而且可以复制原则上呈现许多不同形状、具有许多不同功能特征、并与许多不同类型的化学物种相关联的离散结构。



For a discussion of other chemical bases for hypothetical self-replicating systems, see alternative biochemistry.

For a discussion of other chemical bases for hypothetical self-replicating systems, see alternative biochemistry.

有关假设的自我复制系统的其他化学基础的讨论,请参阅替代生物化学。



See also

See also

参见








  • RepRap (self-replicated 3D printer)














References

References

参考资料

  1. "'Lifeless' prion proteins are 'capable of evolution'". BBC News. 2010-01-01. Retrieved 2013-10-22.
  2. von Neumann, John (1948). The Hixon Symposium. Pasadena, California. pp. 1–36. 
  3. Freitas, Robert; Merkle, Ralph (2004). "Kinematic Self-Replicating Machines - General Taxonomy of Replicators". Retrieved 2013-06-29.
  4. Freitas, Robert; Merkle, Ralph (2004). "Kinematic Self-Replicating Machines - Freitas-Merkle Map of the Kinematic Replicator Design Space (2003–2004)". Retrieved 2013-06-29.
  5. For an image that does not show how this replicates, see: Eric W. Weisstein. "Sphinx." From MathWorld--A Wolfram Web Resource. http://mathworld.wolfram.com/Sphinx.html
  6. For further illustrations, see Teaching TILINGS / TESSELLATIONS with Geo Sphinx
  7. "The idea that life began as clay crystals is 50 years old". bbc.com. 2016-08-24. Retrieved 2019-11-10.
  8. "Modeling Kinematic Cellular Automata Final Report" (PDF). 2004-04-30. Retrieved 2013-10-22.
  9. "Molecular Nanotechnology Guidelines". Foresight.org. Retrieved 2013-10-22.
  10. Moulin, Giuseppone (2011). "Dynamic Combinatorial Self-Replicating Systems". Constitutional Dynamic Chemistry. Topics in Current Chemistry. 322. Springer. pp. 87–105. doi:10.1007/128_2011_198. ISBN 978-3-642-28343-7. PMID 21728135. 
  11. Wikisource:Advanced Automation for Space Missions
  12. Wang, Tong; Sha, Ruojie; Dreyfus, Rémi; Leunissen, Mirjam E.; Maass, Corinna; Pine, David J.; Chaikin, Paul M.; Seeman, Nadrian C. (2011). "Self-replication of information-bearing nanoscale patterns". Nature. 478 (7368): 225–228. doi:10.1038/nature10500. PMC 3192504. PMID 21993758.
  13. "Self-replication process holds promise for production of new materials". Science Daily. 2011-10-17. Retrieved 2011-10-17.


Notes

Notes

注释


  • von Neumann, J., 1966, The Theory of Self-reproducing Automata, A. Burks, ed., Univ. of Illinois Press, Urbana, IL.






  • Kenyon, R., Self-replicating tilings, in: Symbolic Dynamics and Applications (P. Walters, ed.) Contemporary Math. vol. 135 (1992), 239-264.






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