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{{Use American English|date=December 2019}}

{{Use American English|date=December 2019}}

[[File:Champagne vent white smokers.jpg|thumb|upright=1.5|The [[earliest known life forms|earliest known life-forms]] on [[Earth]] are putative fossilized [[microorganism]]s, found in [[Hydrothermal vent|hydrothermal vent precipitates]], that may have lived as early as 4.28 Gya (billion years ago), relatively soon after the [[ocean]]s [[Origin of water on Earth#Water in the development of Earth|formed 4.41 Gya]], and not long after the [[Age of the Earth|formation of the Earth]] 4.54 Gya.<ref name="NAT-20170301" /><ref name="NYT-20170301" />]]

[[File:Champagne vent white smokers.jpg|thumb|upright=1.5|The [[earliest known life forms|earliest known life-forms]] on [[Earth]] are putative fossilized [[microorganism]]s, found in [[Hydrothermal vent|hydrothermal vent precipitates]], that may have lived as early as 4.28 Gya (billion years ago), relatively soon after the [[ocean]]s [[Origin of water on Earth#Water in the development of Earth|formed 4.41 Gya]], and not long after the [[Age of the Earth|formation of the Earth]] 4.54 Gya.

The earliest known life-forms on Earth are putative fossilized microorganisms, found in hydrothermal vent precipitates, that may have lived as early as 4.28 Gya (billion years ago), relatively soon after the oceans formed 4.41 Gya, and not long after the formation of the Earth 4.54 Gya.

The earliest known life-forms on Earth are putative fossilized microorganisms, found in hydrothermal vent precipitates, that may have lived as early as 4.28 Gya (billion years ago), relatively soon after the oceans formed 4.41 Gya, and not long after the formation of the Earth 4.54 Gya.

地球上已知最早的生命形式是在热液喷口沉淀物中发现的假定化石微生物，它们可能早在42.8亿年前就已活着，相对而言，是在44.1亿年前海洋形成的不久之后，以及是45.4亿年前地球形成的不长时间后。

地球上已知最早的生命形式是在热液喷口沉淀物中发现并推断存在的化石微生物，它们可能早在42.8亿年前就已活着，相对而言，是在44.1亿年前海洋形成的不久之后，以及是45.4亿年前地球形成的不长时间后<ref name="NAT-20170301" /><ref name="NYT-20170301" />]]。

In [[evolutionary biology]], '''abiogenesis''', or informally the '''origin of life''' (OoL),<ref>{{cite book| last1 = Oparin| first1 = Aleksandr Ivanovich| author-link1 = Alexander Oparin| translator1-last = Morgulis| translator1-first = Sergius| year = 1938| title = The Origin of Life| url = https://books.google.com/books?id=Jv8psJCtI0gC| series = Phoenix Edition Series| edition = 2| location = Mineola, New York| publisher = Courier Corporation| publication-date = 2003| isbn = 978-0486495224| access-date = 2018-06-16}}</ref><ref name=Pereto /><ref name="AST-20151218">Compare: {{cite journal |author= Scharf, Caleb |title= A Strategy for Origins of Life Research |date= 18 December 2015 |journal= [[Astrobiology (journal)|Astrobiology]] |volume= 15 |issue= 12 |pages= 1031–1042 |doi= 10.1089/ast.2015.1113 |display-authors= etal |pmid= 26684503 |pmc= 4683543|bibcode= 2015AsBio..15.1031S | quote = What do we mean by the origins of life (OoL)? [...] Since the early 20th century the phrase OoL has been used to refer to the events that occurred during the transition from non-living to living systems on Earth, i.e., the origin of terrestrial biology (Oparin, 1924; Haldane, 1929). The term has largely replaced earlier concepts such as abiogenesis (Kamminga, 1980; Fry, 2000).}}</ref>{{efn|Also occasionally called biopoiesis (Bernal, 1960, p. 30)}} is the [[natural]] process by which [[life]] has arisen from non-living matter, such as simple [[organic compound]]s.<ref name=Oparin>{{harvnb|Oparin|1953|p=vi}}</ref><ref name=Pereto>{{cite journal|last= Peretó |first= Juli |year= 2005 |title= Controversies on the origin of life |url= http://www.im.microbios.org/0801/0801023.pdf |journal= [[International Microbiology]] |volume= 8 |issue= 1 |pages= 23–31 |pmid= 15906258 |accessdate= 2015-06-01 |url-status= dead |archiveurl= https://web.archive.org/web/20150824074726/http://www.im.microbios.org/0801/0801023.pdf |archivedate= 24 August 2015 |quote = Ever since the historical contributions by Aleksandr I. Oparin, in the 1920s, the intellectual challenge of the origin of life enigma has unfolded based on the assumption that life originated on Earth through physicochemical processes that can be supposed, comprehended, and simulated; that is, there were neither miracles nor spontaneous generations.}}</ref><ref>{{cite journal |last1= Warmflash |first1= David |last2= Warmflash |first2= Benjamin |date= November 2005 |title= Did Life Come from Another World? |journal= [[Scientific American]] |volume= 293 |issue= 5 |pages= 64–71 |doi= 10.1038/scientificamerican1105-64|pmid= 16318028 |bibcode= 2005SciAm.293e..64W | quote = According to the conventional hypothesis, the earliest living cells emerged as a result of chemical evolution on our planet billions of years ago in a process called abiogenesis.}}</ref><ref>{{harvnb|Yarus|2010|p=47}}</ref> While the details of this process are still unknown, the prevailing scientific hypothesis is that the transition from non-living to living entities was not a single event, but an evolutionary process of increasing complexity that involved molecular [[self-replication]], [[self-assembly]], [[autocatalysis]], and the emergence of [[cell membrane]]s.<ref>{{cite journal|url=http://www.biocommunication.at/pdf/publications/biosystems_2016.pdf |title=Crucial steps to life: From chemical reactions to code using agents|journal=Biosystems|volume=140|pages=49–57|doi=10.1016/j.biosystems.2015.12.007|pmid=26723230|year=2016|last1=Witzany|first1=Guenther}}</ref><ref name="AB-20141208">{{cite web |last= Howell |first= Elizabeth |title= How Did Life Become Complex, And Could It Happen Beyond Earth? |url= https://www.astrobio.net/origin-and-evolution-of-life/life-become-complex-happen-beyond-earth/ |date= 8 December 2014 |work= [[Astrobiology Magazine]] |accessdate= 14 February 2018 }}</ref><ref name="EA-20150420">{{Cite book |last= Tirard |first= Stephane |title= Abiogenesis – Definition|date= 20 April 2015 |doi= 10.1007/978-3-642-27833-4_2-4 |journal= Encyclopedia of Astrobiology|pages= 1 | quote = Thomas Huxley (1825–1895) used the term abiogenesis in an important text published in 1870. He strictly made the difference between spontaneous generation, which he did not accept, and the possibility of the evolution of matter from inert to living, without any influence of life. [...] Since the end of the nineteenth century, evolutive abiogenesis means increasing complexity and evolution of matter from inert to living state in the abiotic context of evolution of primitive Earth. |isbn= 978-3-642-27833-4 }}</ref> Although the occurrence of abiogenesis is uncontroversial among scientists, its possible mechanisms are poorly understood. There are several principles and hypotheses for {{em|how}} abiogenesis could have occurred.<ref>{{Cite book |title=Rethinking evolution: the revolution that's hiding in plain sight  |last=Levinson |first=Gene |publisher=World Scientific |year=2020 |isbn=978-1786347268 |url=https://rethinkingevolution.com/}}</ref>

In [[evolutionary biology]], '''abiogenesis''', or informally the '''origin of life''' (OoL), is the [[natural]] process by which [[life]] has arisen from non-living matter, such as simple [[organic compound]]s. While the details of this process are still unknown, the prevailing scientific hypothesis is that the transition from non-living to living entities was not a single event, but an evolutionary process of increasing complexity that involved molecular [[self-replication]], [[self-assembly]], [[autocatalysis]], and the emergence of [[cell membrane]]s. Although the occurrence of abiogenesis is uncontroversial among scientists, its possible mechanisms are poorly understood. There are several principles and hypotheses for {{em|how}} abiogenesis could have occurred.

In evolutionary biology, abiogenesis, or informally the origin of life (OoL), is the natural process by which life has arisen from non-living matter, such as simple organic compounds. While the details of this process are still unknown, the prevailing scientific hypothesis is that the transition from non-living to living entities was not a single event, but an evolutionary process of increasing complexity that involved molecular self-replication, self-assembly, autocatalysis, and the emergence of cell membranes. Although the occurrence of abiogenesis is uncontroversial among scientists, its possible mechanisms are poorly understood. There are several principles and hypotheses for abiogenesis could have occurred.

In evolutionary biology, abiogenesis, or informally the origin of life (OoL), is the natural process by which life has arisen from non-living matter, such as simple organic compounds. While the details of this process are still unknown, the prevailing scientific hypothesis is that the transition from non-living to living entities was not a single event, but an evolutionary process of increasing complexity that involved molecular self-replication, self-assembly, autocatalysis, and the emergence of cell membranes. Although the occurrence of abiogenesis is uncontroversial among scientists, its possible mechanisms are poorly understood. There are several principles and hypotheses for abiogenesis could have occurred.

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The study of abiogenesis aims to determine how pre-life [[chemical reaction]]s gave rise to life under conditions strikingly different from those on Earth today.<ref>{{harvnb|Voet|Voet|2004|p=29}}</ref> It primarily uses tools from [[biology]], [[chemistry]], and [[geophysics]],<ref name="Dyson 1999">{{harvnb|Dyson|1999}}</ref> with more recent approaches attempting a synthesis of all three:<ref>{{cite book |author= Davies, Paul |date= 1998 |title= The Fifth Miracle, Search for the origin and meaning of life |publisher= Penguin}}{{page needed|date=February 2017}}</ref> more specifically, [[astrobiology]], [[biochemistry]], [[biophysics]], [[geochemistry]], [[molecular biology]], [[oceanography]] and [[paleontology]]. Life functions through the specialized chemistry of [[carbon]] and [[water]] and builds largely upon four key families of chemicals: [[lipids]] (cell membranes), [[carbohydrates]] (sugars, cellulose), [[amino acid]]s (protein metabolism), and [[nucleic acids]] (DNA and RNA). Any successful theory of abiogenesis must explain the origins and interactions of these classes of molecules.<ref>{{cite book |author1= Ward, Peter|author2= Kirschvink, Joe |date= 2015 |title= A New History of Life: the radical discoveries about the origins and evolution of life on earth |publisher= Bloomsbury Press |pages= 39–40 |isbn= 978-1608199105}}</ref> Many approaches to abiogenesis investigate how [[Self-replication|self-replicating]] [[molecule]]s, or their components, came into existence. Researchers generally think that current life descends from an [[RNA world]],<ref name="RNA" /> although other self-replicating molecules may have preceded RNA.<ref name="Robertson2012" /><ref name="Cech2012" />

The study of abiogenesis aims to determine how pre-life [[chemical reaction]]s gave rise to life under conditions strikingly different from those on Earth today.<ref>{{harvnb|Voet|Voet|2004|p=29}}</ref> It primarily uses tools from [[biology]], [[chemistry]], and [[geophysics]], more specifically, [[astrobiology]], [[biochemistry]], [[biophysics]], [[geochemistry]], [[molecular biology]], [[oceanography]] and [[paleontology]]. Life functions through the specialized chemistry of [[carbon]] and [[water]] and builds largely upon four key families of chemicals: [[lipids]] (cell membranes), [[carbohydrates]] (sugars, cellulose), [[amino acid]]s (protein metabolism), and [[nucleic acids]] (DNA and RNA). Any successful theory of abiogenesis must explain the origins and interactions of these classes of molecules.  Many approaches to abiogenesis investigate how [[Self-replication|self-replicating]] [[molecule]]s, or their components, came into existence. Researchers generally think that current life descends from an [[RNA world]],<ref name="RNA" /> although other self-replicating molecules may have preceded RNA.

The study of abiogenesis aims to determine how pre-life chemical reactions gave rise to life under conditions strikingly different from those on Earth today. It primarily uses tools from biology, chemistry, and geophysics, with more recent approaches attempting a synthesis of all three: more specifically, astrobiology, biochemistry, biophysics, geochemistry, molecular biology, oceanography and paleontology. Life functions through the specialized chemistry of carbon and water and builds largely upon four key families of chemicals: lipids (cell membranes), carbohydrates (sugars, cellulose), amino acids (protein metabolism), and nucleic acids (DNA and RNA). Any successful theory of abiogenesis must explain the origins and interactions of these classes of molecules.  Many approaches to abiogenesis investigate how self-replicating molecules, or their components, came into existence. Researchers generally think that current life descends from an RNA world, although other self-replicating molecules may have preceded RNA.

The study of abiogenesis aims to determine how pre-life chemical reactions gave rise to life under conditions strikingly different from those on Earth today. It primarily uses tools from biology, chemistry, and geophysics, with more recent approaches attempting a synthesis of all three: more specifically, astrobiology, biochemistry, biophysics, geochemistry, molecular biology, oceanography and paleontology. Life functions through the specialized chemistry of carbon and water and builds largely upon four key families of chemicals: lipids (cell membranes), carbohydrates (sugars, cellulose), amino acids (protein metabolism), and nucleic acids (DNA and RNA). Any successful theory of abiogenesis must explain the origins and interactions of these classes of molecules.  Many approaches to abiogenesis investigate how self-replicating molecules, or their components, came into existence. Researchers generally think that current life descends from an RNA world, although other self-replicating molecules may have preceded RNA.

[[File:Miller-Urey experiment JP.png|thumb|'''Miller–Urey experiment'''  Synthesis of small organic molecules in a mixture of simple gases that is placed in a thermal gradient by heating (left) and cooling (right) the mixture at the same time, a mixture that is also subject to electrical discharges]]

[[File:Miller-Urey experiment JP.png|thumb|'''Miller–Urey experiment'''  Synthesis of small organic molecules in a mixture of simple gases that is placed in a thermal gradient by heating (left) and cooling (right) the mixture at the same time, a mixture that is also subject to electrical discharges]]

Miller–Urey experiment Synthesis of small organic molecules in a mixture of simple gases that is placed in a thermal gradient by heating (left) and cooling (right) the mixture at the same time, a mixture that is also subject to electrical discharges

Miller–Urey experiment Synthesis of small organic molecules in a mixture of simple gases that is placed in a thermal gradient by heating (left) and cooling (right) the mixture at the same time, a mixture that is also subject to electrical discharges

米勒-尤里Miller–Urey实验 在简单气体混合物中合成小有机分子，将混合物置于热梯度中，同时加热（左）和冷却（右），这种混合物也会受到电的作用

米勒-尤里Miller–Urey实验 将简单气体混合物置于有热梯度的环境中，同时加热（左）和冷却（右），并施加电的作用，这种条件下能够合成小有机分子。

The classic 1952 [[Miller–Urey experiment]] and similar research demonstrated that most amino acids, the chemical constituents of the [[protein]]s used in all living organisms, can be synthesized from [[inorganic compound]]s under conditions intended to replicate those of the [[History of Earth|early Earth]]. Scientists have proposed various external sources of energy that may have triggered these reactions, including [[lightning]] and [[radiation]]. Other approaches ("metabolism-first" hypotheses) focus on understanding how [[catalysis]] in chemical systems on the early Earth might have provided the [[Precursor (chemistry)|precursor molecules]] necessary for self-replication.<ref name="Ralser 2014">{{cite journal |last1= Keller |first1= Markus A. |last2= Turchyn |first2= Alexandra V. |last3= Ralser |first3= Markus |date= 25 March 2014 |title= Non‐enzymatic glycolysis and pentose phosphate pathway‐like reactions in a plausible Archean ocean |journal= [[Molecular Systems Biology]] |volume= 10 |issue= 725 |page= 725 |doi= 10.1002/msb.20145228 |pmc= 4023395 |pmid= 24771084}}</ref>

The classic 1952 [[Miller–Urey experiment]] and similar research demonstrated that most amino acids, the chemical constituents of the [[protein]]s used in all living organisms, can be synthesized from [[inorganic compound]]s under conditions intended to replicate those of the [[History of Earth|early Earth]]. Scientists have proposed various external sources of energy that may have triggered these reactions, including [[lightning]] and [[radiation]]. Other approaches ("metabolism-first" hypotheses) focus on understanding how [[catalysis]] in chemical systems on the early Earth might have provided the [[Precursor (chemistry)|precursor molecules]] necessary for self-replication.

The classic 1952 Miller–Urey experiment and similar research demonstrated that most amino acids, the chemical constituents of the proteins used in all living organisms, can be synthesized from inorganic compounds under conditions intended to replicate those of the early Earth. Scientists have proposed various external sources of energy that may have triggered these reactions, including lightning and radiation. Other approaches ("metabolism-first" hypotheses) focus on understanding how catalysis in chemical systems on the early Earth might have provided the precursor molecules necessary for self-replication.

The classic 1952 Miller–Urey experiment and similar research demonstrated that most amino acids, the chemical constituents of the proteins used in all living organisms, can be synthesized from inorganic compounds under conditions intended to replicate those of the early Earth. Scientists have proposed various external sources of energy that may have triggered these reactions, including lightning and radiation. Other approaches ("metabolism-first" hypotheses) focus on understanding how catalysis in chemical systems on the early Earth might have provided the precursor molecules necessary for self-replication.

1952年经典的Miller-Urey实验和类似的研究表明，大多数氨基酸，即所有生物体中使用的蛋白质的化学成分，可以在旨在复制早期地球的条件下从无机化合物中合成。科学家们提出了各种可能引发这些反应的外部能量来源，包括闪电和辐射。其他方法("新陈代谢优先 "假说)则侧重于了解早期地球化学系统中的催化作用如何提供自我复制所需的前体分子。

1952年经典的Miller-Urey实验和类似的研究表明，大多数氨基酸（即所有生物体中使用的蛋白质的化学成分）可以在复制早期地球环境的条件下从无机化合物中合成。科学家们提出了各种可能引发这些反应的外部能量来源，包括闪电和辐射。其他方法("新陈代谢优先 "假说)则侧重于了解早期地球化学系统中的催化作用如何提供自我复制所需的前体分子。<ref name="Ralser 2014">{{cite journal |last1= Keller |first1= Markus A. |last2= Turchyn |first2= Alexandra V. |last3= Ralser |first3= Markus |date= 25 March 2014 |title= Non‐enzymatic glycolysis and pentose phosphate pathway‐like reactions in a plausible Archean ocean |journal= [[Molecular Systems Biology]] |volume= 10 |issue= 725 |page= 725 |doi= 10.1002/msb.20145228 |pmc= 4023395 |pmid= 24771084}}</ref>

The alternative [[panspermia hypothesis]]<ref name="USRA-2010">{{cite conference|last=Rampelotto|first=Pabulo Henrique|date=26 April 2010|title=Panspermia: A Promising Field of Research|url=http://www.lpi.usra.edu/meetings/abscicon2010/pdf/5224.pdf|url-status=live|conference=Astrobiology Science Conference 2010|location=Houston, TX|publisher=[[Lunar and Planetary Institute]]|page=5224|bibcode=2010LPICo1538.5224R|archiveurl=https://web.archive.org/web/20160327005016/http://www.lpi.usra.edu//meetings/abscicon2010/pdf/5224.pdf|archivedate=27 March 2016|accessdate=2014-12-03|conference-url=http://www.lpi.usra.edu/meetings/abscicon2010/}} Conference held at League City, TX</ref> speculates that [[Microorganism|microscopic life]] arose outside Earth by unknown mechanisms, and spread to the early Earth on [[space dust]]<ref name="ARX-20171106">{{cite journal |last= Berera |first= Arjun |title= Space dust collisions as a planetary escape mechanism |journal= Astrobiology |date= 6 November 2017 |arxiv= 1711.01895 |bibcode= 2017AsBio..17.1274B |doi= 10.1089/ast.2017.1662 |pmid= 29148823 |volume= 17 |issue= 12 |pages= 1274–1282|s2cid= 126012488 }}</ref> and [[meteoroid]]s.<ref name="SA-20180110">{{cite journal|last1=Chan|first1=Queenie H.S.|date=10 January 2018|title=Organic matter in extraterrestrial water-bearing salt crystals|journal=[[Science Advances]]|volume=4|page=eaao3521|bibcode=2018SciA....4O3521C|doi=10.1126/sciadv.aao3521|pmc=5770164|pmid=29349297|number=1, eaao3521}}</ref> It is known that complex [[List of interstellar and circumstellar molecules|organic molecules]] occur in the [[Solar System]] and in [[interstellar space]], and these molecules may have provided [[Precursor (chemistry)|starting material]] for the development of life on Earth.<ref name="Ehrenfreund2010" /><ref name="Science 2015">{{cite news|url=http://news.sciencemag.org/chemistry/2015/04/organic-molecules-found-circling-nearby-star?rss=1|title=Organic molecules found circling nearby star|last=Perkins|first=Sid|date=8 April 2015|work=[[Science (journal)|Science]]|accessdate=2015-06-02|publisher=[[American Association for the Advancement of Science]]|location=Washington, DC|type=News}}</ref><ref>{{cite news|url=http://www.rsc.org/chemistryworld/2015/04/meteorites-may-have-delivered-chemicals-started-life-earth|title=Chemicals formed on meteorites may have started life on Earth|last=King|first=Anthony|date=14 April 2015|work=[[Chemistry World]]|accessdate=2015-04-17|archiveurl=https://web.archive.org/web/20150417142723/http://www.rsc.org/chemistryworld/2015/04/meteorites-may-have-delivered-chemicals-started-life-earth|archivedate=17 April 2015|url-status=live|publisher=[[Royal Society of Chemistry]]|location=London|type=News}}</ref><ref>{{cite journal|last1=Saladino|first1=Raffaele|last2=Carota|first2=Eleonora|last3=Botta|first3=Giorgia|last4=Kapralov|first4=Mikhail|last5=Timoshenko|first5=Gennady N.|last6=Rozanov|first6=Alexei Y.|last7=Krasavin|first7=Eugene|last8=Di Mauro|first8=Ernesto|display-authors=3|date=13 April 2015|title=Meteorite-catalyzed syntheses of nucleosides and of other prebiotic compounds from formamide under proton irradiation|journal=[[Proceedings of the National Academy of Sciences of the United States of America|Proc. Natl. Acad. Sci. U.S.A.]]|volume=112|issue=21|pages=E2746–E2755|bibcode=2015PNAS..112E2746S|doi=10.1073/pnas.1422225112|pmc=4450408|pmid=25870268}}</ref>

The alternative [[panspermia hypothesis]] speculates that [[Microorganism|microscopic life]] arose outside Earth by unknown mechanisms, and spread to the early Earth on [[space dust]] and [[meteoroid]]s. It is known that complex [[List of interstellar and circumstellar molecules|organic molecules]] occur in the [[Solar System]] and in [[interstellar space]], and these molecules may have provided [[Precursor (chemistry)|starting material]] for the development of life on Earth.

The alternative panspermia hypothesis speculates that microscopic life arose outside Earth by unknown mechanisms, and spread to the early Earth on space dust and meteoroids. It is known that complex organic molecules occur in the Solar System and in interstellar space, and these molecules may have provided starting material for the development of life on Earth.

The alternative panspermia hypothesis speculates that microscopic life arose outside Earth by unknown mechanisms, and spread to the early Earth on space dust and meteoroids. It is known that complex organic molecules occur in the Solar System and in interstellar space, and these molecules may have provided starting material for the development of life on Earth.

Earth remains the only place in the [[universe]] known to harbour life,<ref name="NASA-1990">{{cite web |url= https://ntrs.nasa.gov/archive/nasa/casi.ntrs.nasa.gov/19900013148.pdf |title= Extraterrestrial Life in the Universe |last= Graham |first= Robert W. |date= February 1990 |place= [[Glenn Research Center|Lewis Research Center]], Cleveland, Ohio |publisher= [[NASA]] |type= NASA Technical Memorandum 102363 |accessdate= 2015-06-02 |url-status= live |archiveurl= https://web.archive.org/web/20140903100534/http://ntrs.nasa.gov/archive/nasa/casi.ntrs.nasa.gov/19900013148.pdf |archivedate= 3 September 2014}}</ref><ref>{{harvnb|Altermann|2009|p=xvii}}</ref> and [[Earliest known life forms|fossil evidence from the Earth]] informs most studies of abiogenesis. The [[age of the Earth]] is 4.54 Gy (Giga or billion year);<ref name="USGS1997">{{cite web |url= http://pubs.usgs.gov/gip/geotime/age.html |title= Age of the Earth |date= 9 July 2007 |publisher= [[United States Geological Survey]] |accessdate= 2006-01-10 |url-status= live |archiveurl= https://web.archive.org/web/20051223072700/http://pubs.usgs.gov/gip/geotime/age.html |archivedate= 23 December 2005}}</ref><ref>{{harvnb|Dalrymple|2001|pp= 205–221}}</ref><ref>{{cite journal |last1= Manhesa |first1= Gérard |last2= Allègre |first2= Claude J. |authorlink2= Claude Allègre |last3= Dupréa |first3= Bernard |last4= Hamelin |first4= Bruno |date= May 1980 |title= Lead isotope study of basic-ultrabasic layered complexes: Speculations about the age of the earth and primitive mantle characteristics |journal= [[Earth and Planetary Science Letters]] |volume= 47 |issue= 3 |pages= 370–382 |bibcode= 1980E&PSL..47..370M |doi= 10.1016/0012-821X(80)90024-2 }}</ref> the earliest undisputed evidence of life on Earth dates from at least 3.5 Gya (Gy ago),<ref name="Origin1">{{cite journal |last1= Schopf |first1= J. William |authorlink1= J. William Schopf |last2= Kudryavtsev |first2= Anatoliy B. |last3= Czaja |first3= Andrew D. |last4= Tripathi |first4= Abhishek B. |date= 5 October 2007 |title= Evidence of Archean life: Stromatolites and microfossils |journal= [[Precambrian Research]] |volume= 158 |pages= 141–155 |issue= 3–4 |doi= 10.1016/j.precamres.2007.04.009 |bibcode= 2007PreR..158..141S }}</ref><ref name="Origin2">{{cite journal |last= Schopf |first= J. William |date= 29 June 2006 |title= Fossil evidence of Archaean life |journal= [[Philosophical Transactions of the Royal Society B]] |volume= 361 |issue= 1470 |pages= 869–885 |doi= 10.1098/rstb.2006.1834 |pmid= 16754604 |pmc=1578735}}</ref><ref name="RavenJohnson2002">{{harvnb|Raven|Johnson|2002|p=68}}</ref> and possibly as early as the [[Eoarchean]] Era (3.6-4.0 Gya). In 2017 scientists found possible evidence of early life [[Evolutionary history of life#Colonization of land|on land]] in 3.48 Gyo (Gy old) [[geyserite]] and other related mineral deposits (often found around [[hot spring]]s and [[geyser]]s) uncovered in the [[Pilbara Craton]] of [[Western Australia]].<ref name="PO-20170509">{{cite news |author= Staff |title= Oldest evidence of life on land found in 3.48-billion-year-old Australian rocks |url= https://phys.org/news/2017-05-oldest-evidence-life-billion-year-old-australian.html |date= 9 May 2017 |work= [[Phys.org]] |accessdate= 13 May 2017 |url-status= live |archiveurl= https://web.archive.org/web/20170510013721/https://phys.org/news/2017-05-oldest-evidence-life-billion-year-old-australian.html |archivedate= 10 May 2017}}</ref><ref name="NC-20170509">{{cite journal |last1= Djokic |first1= Tara |last2= Van Kranendonk |first2= Martin J. |last3= Campbell |first3= Kathleen A. |last4= Walter |first4= Malcolm R. |last5= Ward |first5= Colin R. |title= Earliest signs of life on land preserved in ca. 3.5 Gao hot spring deposits |date= 9 May 2017 |journal= [[Nature Communications]] |doi= 10.1038/ncomms15263 |pmid= 28486437 |pmc= 5436104 |volume= 8 |page= 15263 |bibcode= 2017NatCo...815263D}}</ref><ref name="PNAS-2017">{{cite journal |last1= Schopf |first1= J. William |last2= Kitajima |first2= Kouki |last3= Spicuzza |first3= Michael J. |last4= Kudryavtsev |first4= Anatolly B. |last5= Valley |first5= John W. |title= SIMS analyses of the oldest known assemblage of microfossils document their taxon-correlated carbon isotope compositions |date= 2017 |journal= [[Proceedings of the National Academy of Sciences of the United States of America|PNAS]] |doi= 10.1073/pnas.1718063115 |pmid= 29255053 |pmc= 5776830 |volume= 115 |issue= 1 |pages= 53–58|bibcode= 2018PNAS..115...53S }}</ref><ref name="WU-20171218">{{cite web |last= Tyrell |first= Kelly April |title= Oldest fossils ever found show life on Earth began before 3.5 billion years ago |url= https://news.wisc.edu/oldest-fossils-ever-found-show-life-on-earth-began-before-3-5-billion-years-ago/ |date= 18 December 2017 |work= [[University of Wisconsin-Madison]] |accessdate= 18 December 2017 }}</ref> However, a number of discoveries suggest that life may have appeared on Earth even earlier. {{As of | 2017}}, [[Micropaleontology#Microfossils|microfossils]] (fossilised [[microorganism]]s) within [[Hydrothermal vent|hydrothermal-vent precipitates]] dated 3.77 to 4.28 Gya in rocks in [[Quebec]] may harbour the oldest record of life on Earth, suggesting life started soon after [[Origin of water on Earth#Water in the development of Earth|ocean formation 4.4 Gya]] during the [[Hadean]] [[Geologic time scale|Eon]].<ref name="NAT-20170301">{{cite journal |last1= Dodd |first1= Matthew S. |last2= Papineau |first2= Dominic |last3= Grenne |first3= Tor |last4= Slack |first4= John F. |last5= Rittner |first5= Martin |last6= Pirajno |first6= Franco |last7= O'Neil |first7= Jonathan |last8= Little |first8= Crispin T.S. |title= Evidence for early life in Earth's oldest hydrothermal vent precipitates |url= http://eprints.whiterose.ac.uk/112179/ |journal= [[Nature (journal)|Nature]] |date= 1 March 2017 |volume= 543 |issue= 7643 |pages= 60–64 |doi= 10.1038/nature21377 |pmid= 28252057 |accessdate= 2 March 2017 |bibcode= 2017Natur.543...60D |url-status= live |archiveurl= https://web.archive.org/web/20170908201821/http://eprints.whiterose.ac.uk/112179/ |archivedate= 8 September 2017|doi-access= free }}</ref><ref name="NYT-20170301">{{cite news |last= Zimmer |first= Carl |authorlink= Carl Zimmer |title= Scientists Say Canadian Bacteria Fossils May Be Earth's Oldest |url= https://www.nytimes.com/2017/03/01/science/earths-oldest-bacteria-fossils.html |date= 1 March 2017 |work= [[The New York Times]] |accessdate= 2 March 2017 |url-status= live |archiveurl= https://web.archive.org/web/20170302042424/https://www.nytimes.com/2017/03/01/science/earths-oldest-bacteria-fossils.html |archivedate= 2 March 2017}}</ref><ref name="BBC-20170301">{{Cite news |last= Ghosh |first= Pallab |title= Earliest evidence of life on Earth found |url= https://www.bbc.co.uk/news/science-environment-39117523 |publisher= [[BBC News]] |date= 1 March 2017 |accessdate= 2 March 2017 |url-status= live |archiveurl= https://web.archive.org/web/20170302002134/http://www.bbc.co.uk/news/science-environment-39117523 |archivedate= 2 March 2017|work= BBC News }}</ref><ref name="4.3b oldest">{{cite news |last1= Dunham |first1= Will |title= Canadian bacteria-like fossils called oldest evidence of life |url= http://ca.reuters.com/article/topNews/idCAKBN16858B?sp=true |date= 1 March 2017 |agency= [[Reuters]] |accessdate= 1 March 2017 |url-status= live |archiveurl= https://web.archive.org/web/20170302114728/http://ca.reuters.com/article/topNews/idCAKBN16858B?sp=true |archivedate= 2 March 2017}}</ref><ref>{{cite news|title=Researchers uncover 'direct evidence' of life on Earth 4 billion years ago|url= http://dw.com/p/2YUnT|accessdate= 5 March 2017|publisher= Deutsche Welle}}</ref>

Earth remains the only place in the [[universe]] known to harbour life, and [[Earliest known life forms|fossil evidence from the Earth]] informs most studies of abiogenesis. The [[age of the Earth]] is 4.54 Gy (Giga or billion year); the earliest undisputed evidence of life on Earth dates from at least 3.5 Gya (Gy ago), and possibly as early as the [[Eoarchean]] Era (3.6-4.0 Gya). In 2017 scientists found possible evidence of early life [[Evolutionary history of life#Colonization of land|on land]] in 3.48 Gyo (Gy old) [[geyserite]] and other related mineral deposits (often found around [[hot spring]]s and [[geyser]]s) uncovered in the [[Pilbara Craton]] of [[Western Australia]]. However, a number of discoveries suggest that life may have appeared on Earth even earlier. {{As of | 2017}}, [[Micropaleontology#Microfossils|microfossils]] (fossilised [[microorganism]]s) within [[Hydrothermal vent|hydrothermal-vent precipitates]] dated 3.77 to 4.28 Gya in rocks in [[Quebec]] may harbour the oldest record of life on Earth, suggesting life started soon after [[Origin of water on Earth#Water in the development of Earth|ocean formation 4.4 Gya]] during the [[Hadean]] [[Geologic time scale|Eon]].

Earth remains the only place in the universe known to harbour life, and fossil evidence from the Earth informs most studies of abiogenesis. The age of the Earth is 4.54 Gy (Giga or billion year); the earliest undisputed evidence of life on Earth dates from at least 3.5 Gya (Gy ago), and possibly as early as the Eoarchean Era (3.6-4.0 Gya). In 2017 scientists found possible evidence of early life on land in 3.48 Gyo (Gy old) geyserite and other related mineral deposits (often found around hot springs and geysers) uncovered in the Pilbara Craton of Western Australia. However, a number of discoveries suggest that life may have appeared on Earth even earlier. , microfossils (fossilised microorganisms) within hydrothermal-vent precipitates dated 3.77 to 4.28 Gya in rocks in Quebec may harbour the oldest record of life on Earth, suggesting life started soon after ocean formation 4.4 Gya during the Hadean Eon.

Earth remains the only place in the universe known to harbour life, and fossil evidence from the Earth informs most studies of abiogenesis. The age of the Earth is 4.54 Gy (Giga or billion year); the earliest undisputed evidence of life on Earth dates from at least 3.5 Gya (Gy ago), and possibly as early as the Eoarchean Era (3.6-4.0 Gya). In 2017 scientists found possible evidence of early life on land in 3.48 Gyo (Gy old) geyserite and other related mineral deposits (often found around hot springs and geysers) uncovered in the Pilbara Craton of Western Australia. However, a number of discoveries suggest that life may have appeared on Earth even earlier. , microfossils (fossilised microorganisms) within hydrothermal-vent precipitates dated 3.77 to 4.28 Gya in rocks in Quebec may harbour the oldest record of life on Earth, suggesting life started soon after ocean formation 4.4 Gya during the Hadean Eon.

地球仍然是宇宙中已知的唯一一个孕育生命的地方，来自地球的化石证据为大多数关于自然发生的研究提供了依据。地球的年龄是45.5亿年 (千兆或十亿年) ; 地球上最早的无可争议的生命证据至少可以追溯到35亿年前，也可能还要追溯到早期太古代(36-40亿年前之间)。2017年，科学家在西澳大利亚的 皮尔巴拉环形山发现的34.8亿岁的喷泉石和其他相关矿藏(通常在温泉和喷泉附近发现) 中发现了陆地上早期生命存在的可能证据。然而，许多发现表明，地球上的生命可能出现得更早。截止2017年，在加拿大魁北克省的岩石中的热液喷口沉淀物内的微化石(微生物化石)的年代为37.7亿年前至42.8亿年前，可能蕴藏着地球上最古老的生命记录，这表明生命是在冥古宙海洋形成后不久就开始了。

地球仍然是宇宙中已知的唯一一个孕育生命的地方<ref name="NASA-1990">{{cite web |url= https://ntrs.nasa.gov/archive/nasa/casi.ntrs.nasa.gov/19900013148.pdf |title= Extraterrestrial Life in the Universe |last= Graham |first= Robert W. |date= February 1990 |place= [[Glenn Research Center|Lewis Research Center]], Cleveland, Ohio |publisher= [[NASA]] |type= NASA Technical Memorandum 102363 |accessdate= 2015-06-02 |url-status= live |archiveurl= https://web.archive.org/web/20140903100534/http://ntrs.nasa.gov/archive/nasa/casi.ntrs.nasa.gov/19900013148.pdf |archivedate= 3 September 2014}}</ref><ref>{{harvnb|Altermann|2009|p=xvii}}</ref>，来自地球的化石证据为大多数关于无生源说的研究提供了依据。地球的年龄是45.5亿年 (千兆或十亿年) ; <ref name="USGS1997">{{cite web |url= http://pubs.usgs.gov/gip/geotime/age.html |title= Age of the Earth |date= 9 July 2007 |publisher= [[United States Geological Survey]] |accessdate= 2006-01-10 |url-status= live |archiveurl= https://web.archive.org/web/20051223072700/http://pubs.usgs.gov/gip/geotime/age.html |archivedate= 23 December 2005}}</ref><ref>{{harvnb|Dalrymple|2001|pp= 205–221}}</ref><ref>{{cite journal |last1= Manhesa |first1= Gérard |last2= Allègre |first2= Claude J. |authorlink2= Claude Allègre |last3= Dupréa |first3= Bernard |last4= Hamelin |first4= Bruno |date= May 1980 |title= Lead isotope study of basic-ultrabasic layered complexes: Speculations about the age of the earth and primitive mantle characteristics |journal= [[Earth and Planetary Science Letters]] |volume= 47 |issue= 3 |pages= 370–382 |bibcode= 1980E&PSL..47..370M |doi= 10.1016/0012-821X(80)90024-2 }}</ref>地球上最早的无可争议的生命证据至少可以追溯到35亿年前，<ref name="Origin1">{{cite journal |last1= Schopf |first1= J. William |authorlink1= J. William Schopf |last2= Kudryavtsev |first2= Anatoliy B. |last3= Czaja |first3= Andrew D. |last4= Tripathi |first4= Abhishek B. |date= 5 October 2007 |title= Evidence of Archean life: Stromatolites and microfossils |journal= [[Precambrian Research]] |volume= 158 |pages= 141–155 |issue= 3–4 |doi= 10.1016/j.precamres.2007.04.009 |bibcode= 2007PreR..158..141S }}</ref><ref name="Origin2">{{cite journal |last= Schopf |first= J. William |date= 29 June 2006 |title= Fossil evidence of Archaean life |journal= [[Philosophical Transactions of the Royal Society B]] |volume= 361 |issue= 1470 |pages= 869–885 |doi= 10.1098/rstb.2006.1834 |pmid= 16754604 |pmc=1578735}}</ref><ref name="RavenJohnson2002">{{harvnb|Raven|Johnson|2002|p=68}}</ref>也可能还要追溯到始太古代(36-40亿年前之间)。2017年，科学家在西澳大利亚的皮尔巴拉环形山裸露的34.8亿岁的硅华和其他相关矿藏(通常在温泉和喷泉附近发现) 中发现了陆地上早期生命存在的可能证据。<ref name="PO-20170509">{{cite news |author= Staff |title= Oldest evidence of life on land found in 3.48-billion-year-old Australian rocks |url= https://phys.org/news/2017-05-oldest-evidence-life-billion-year-old-australian.html |date= 9 May 2017 |work= [[Phys.org]] |accessdate= 13 May 2017 |url-status= live |archiveurl= https://web.archive.org/web/20170510013721/https://phys.org/news/2017-05-oldest-evidence-life-billion-year-old-australian.html |archivedate= 10 May 2017}}</ref><ref name="NC-20170509">{{cite journal |last1= Djokic |first1= Tara |last2= Van Kranendonk |first2= Martin J. |last3= Campbell |first3= Kathleen A. |last4= Walter |first4= Malcolm R. |last5= Ward |first5= Colin R. |title= Earliest signs of life on land preserved in ca. 3.5 Gao hot spring deposits |date= 9 May 2017 |journal= [[Nature Communications]] |doi= 10.1038/ncomms15263 |pmid= 28486437 |pmc= 5436104 |volume= 8 |page= 15263 |bibcode= 2017NatCo...815263D}}</ref><ref name="PNAS-2017">{{cite journal |last1= Schopf |first1= J. William |last2= Kitajima |first2= Kouki |last3= Spicuzza |first3= Michael J. |last4= Kudryavtsev |first4= Anatolly B. |last5= Valley |first5= John W. |title= SIMS analyses of the oldest known assemblage of microfossils document their taxon-correlated carbon isotope compositions |date= 2017 |journal= [[Proceedings of the National Academy of Sciences of the United States of America|PNAS]] |doi= 10.1073/pnas.1718063115 |pmid= 29255053 |pmc= 5776830 |volume= 115 |issue= 1 |pages= 53–58|bibcode= 2018PNAS..115...53S }}</ref><ref name="WU-20171218">{{cite web |last= Tyrell |first= Kelly April |title= Oldest fossils ever found show life on Earth began before 3.5 billion years ago |url= https://news.wisc.edu/oldest-fossils-ever-found-show-life-on-earth-began-before-3-5-billion-years-ago/ |date= 18 December 2017 |work= [[University of Wisconsin-Madison]] |accessdate= 18 December 2017 }}</ref>然而，许多发现表明，地球上的生命可能出现得更早。截止2017年，在加拿大魁北克省的岩石中的深海热液喷口沉淀物内的微化石(微生物化石)的年代为37.7亿年前至42.8亿年前，它可能蕴藏着地球上最古老的生命记录，这表明生命在海洋形成后不久的冥古宙就开始了。<ref name="NAT-20170301">{{cite journal |last1= Dodd |first1= Matthew S. |last2= Papineau |first2= Dominic |last3= Grenne |first3= Tor |last4= Slack |first4= John F. |last5= Rittner |first5= Martin |last6= Pirajno |first6= Franco |last7= O'Neil |first7= Jonathan |last8= Little |first8= Crispin T.S. |title= Evidence for early life in Earth's oldest hydrothermal vent precipitates |url= http://eprints.whiterose.ac.uk/112179/ |journal= [[Nature (journal)|Nature]] |date= 1 March 2017 |volume= 543 |issue= 7643 |pages= 60–64 |doi= 10.1038/nature21377 |pmid= 28252057 |accessdate= 2 March 2017 |bibcode= 2017Natur.543...60D |url-status= live |archiveurl= https://web.archive.org/web/20170908201821/http://eprints.whiterose.ac.uk/112179/ |archivedate= 8 September 2017|doi-access= free }}</ref><ref name="NYT-20170301">{{cite news |last= Zimmer |first= Carl |authorlink= Carl Zimmer |title= Scientists Say Canadian Bacteria Fossils May Be Earth's Oldest |url= https://www.nytimes.com/2017/03/01/science/earths-oldest-bacteria-fossils.html |date= 1 March 2017 |work= [[The New York Times]] |accessdate= 2 March 2017 |url-status= live |archiveurl= https://web.archive.org/web/20170302042424/https://www.nytimes.com/2017/03/01/science/earths-oldest-bacteria-fossils.html |archivedate= 2 March 2017}}</ref><ref name="BBC-20170301">{{Cite news |last= Ghosh |first= Pallab |title= Earliest evidence of life on Earth found |url= https://www.bbc.co.uk/news/science-environment-39117523 |publisher= [[BBC News]] |date= 1 March 2017 |accessdate= 2 March 2017 |url-status= live |archiveurl= https://web.archive.org/web/20170302002134/http://www.bbc.co.uk/news/science-environment-39117523 |archivedate= 2 March 2017|work= BBC News }}</ref><ref name="4.3b oldest">{{cite news |last1= Dunham |first1= Will |title= Canadian bacteria-like fossils called oldest evidence of life |url= http://ca.reuters.com/article/topNews/idCAKBN16858B?sp=true |date= 1 March 2017 |agency= [[Reuters]] |accessdate= 1 March 2017 |url-status= live |archiveurl= https://web.archive.org/web/20170302114728/http://ca.reuters.com/article/topNews/idCAKBN16858B?sp=true |archivedate= 2 March 2017}}</ref><ref>{{cite news|title=Researchers uncover 'direct evidence' of life on Earth 4 billion years ago|url= http://dw.com/p/2YUnT|accessdate= 5 March 2017|publisher= Deutsche Welle}}</ref>

The NASA strategy on abiogenesis states that it is necessary to identify interactions, intermediary structures and functions, energy sources, and environmental factors that contributed to the diversity, selection, and replication of evolvable macromolecular systems.<ref name="NASA strategy 2015">{{cite web|url=https://nai.nasa.gov/media/medialibrary/2015/10/NASA_Astrobiology_Strategy_2015_151008.pdf|title=NASA Astrobiology Strategy|year=2015|work=NASA|url-status=dead|archiveurl=https://web.archive.org/web/20161222190306/https://nai.nasa.gov/media/medialibrary/2015/10/NASA_Astrobiology_Strategy_2015_151008.pdf|archivedate=22 December 2016|access-date=24 September 2017}}</ref> Emphasis must continue to map the chemical landscape of potential primordial informational [[polymers]]. The advent of polymers that could replicate, store genetic information, and exhibit properties subject to selection likely was a critical step in the [[emergence]] of prebiotic chemical evolution.<ref name="NASA strategy 2015"/>

The NASA strategy on abiogenesis states that it is necessary to identify interactions, intermediary structures and functions, energy sources, and environmental factors that contributed to the diversity, selection, and replication of evolvable macromolecular systems. Emphasis must continue to map the chemical landscape of potential primordial informational [[polymers]]. The advent of polymers that could replicate, store genetic information, and exhibit properties subject to selection likely was a critical step in the [[emergence]] of prebiotic chemical evolution.

The NASA strategy on abiogenesis states that it is necessary to identify interactions, intermediary structures and functions, energy sources, and environmental factors that contributed to the diversity, selection, and replication of evolvable macromolecular systems. Emphasis must continue to map the chemical landscape of potential primordial informational polymers. The advent of polymers that could replicate, store genetic information, and exhibit properties subject to selection likely was a critical step in the emergence of prebiotic chemical evolution.

The NASA strategy on abiogenesis states that it is necessary to identify interactions, intermediary structures and functions, energy sources, and environmental factors that contributed to the diversity, selection, and replication of evolvable macromolecular systems. Emphasis must continue to map the chemical landscape of potential primordial informational polymers. The advent of polymers that could replicate, store genetic information, and exhibit properties subject to selection likely was a critical step in the emergence of prebiotic chemical evolution.

美国宇航局关于自然发生的战略指出，有必要确定相互作用、中间结构和功能、能源和环境因素，这些因素有助于可进化的大分子系统的多样性、选择和复制.必须继续强调绘制潜在的原始信息聚合物的化学景观。能够复制、储存遗传信息并表现出受选择的特性的聚合物的出现，很可能是前生物化学进化出现的关键一步。

美国宇航局关于无生源说的战略指出，有必要确定相互作用、中间结构和功能、能源和环境这些导致可进化的大分子系统的多样性、选择和复制的因素<ref name="NASA strategy 2015">{{cite web|url=https://nai.nasa.gov/media/medialibrary/2015/10/NASA_Astrobiology_Strategy_2015_151008.pdf|title=NASA Astrobiology Strategy|year=2015|work=NASA|url-status=dead|archiveurl=https://web.archive.org/web/20161222190306/https://nai.nasa.gov/media/medialibrary/2015/10/NASA_Astrobiology_Strategy_2015_151008.pdf|archivedate=22 December 2016|access-date=24 September 2017}}</ref>。必须继续强调构建潜在的原始信息聚合物的化学景观。能够复制、储存遗传信息并表现出受选择的特性的聚合物的出现，很可能是前生物化学演化出现的关键一步。<ref name="NASA strategy 2015"/>

热力学原理：能量与熵

热力学原理：能量与熵

In antiquity it was commonly thought, for instance by Empedocles and Aristotle, that the life of the individuals of some species, and more generally, life itself, could start with high temperature, i.e. implicitly by thermal cycling.<ref>{{cite book|title=In the beginning: Some Greek views on the origins of life and the early state of man |year= 1957|last1= Guthrie|first1= W. K. C.|publisher=Methuen, London}}</ref>

In antiquity it was commonly thought, for instance by Empedocles and Aristotle, that the life of the individuals of some species, and more generally, life itself, could start with high temperature, i.e. implicitly by thermal cycling.

In antiquity it was commonly thought, for instance by Empedocles and Aristotle, that the life of the individuals of some species, and more generally, life itself, could start with high temperature, i.e. implicitly by thermal cycling.

In antiquity it was commonly thought, for instance by Empedocles and Aristotle, that the life of the individuals of some species, and more generally, life itself, could start with high temperature, i.e. implicitly by thermal cycling.

在古代，人们普遍认为，例如恩培多克勒Empedocles和亚里士多德Aristotle就认为，某些物种个体的生命，更普遍地说是生命本身，可以从高温开始，即隐含着热循环。

在古代，人们普遍认为，例如恩培多克勒Empedocles和亚里士多德Aristotle就认为，某些物种个体的生命，更普遍地说是生命本身，可以从高温开始，即隐含着热循环。<ref>{{cite book|title=In the beginning: Some Greek views on the origins of life and the early state of man |year= 1957|last1= Guthrie|first1= W. K. C.|publisher=Methuen, London}}</ref>

Similarly, it was realized early on that life requires a loss of [[entropy]], or disorder, when molecules organize themselves into living matter. This [[Second law of thermodynamics|Second Law of thermodynamics]] needs to be considered when self-organization of matter to higher complexity happens. Because living organisms are machines,<ref>{{cite book| last1 = Simon| first1 = Michael A. | year = 1971| title = The Matter of Life | edition = 1| location = New Haven and London| publisher = Yale University Press}}</ref> the Second Law applies to life as well.

Similarly, it was realized early on that life requires a loss of [[entropy]], or disorder, when molecules organize themselves into living matter. This [[Second law of thermodynamics|Second Law of thermodynamics]] needs to be considered when self-organization of matter to higher complexity happens. Because living organisms are machines, the Second Law applies to life as well.

Similarly, it was realized early on that life requires a loss of entropy, or disorder, when molecules organize themselves into living matter. This Second Law of thermodynamics needs to be considered when self-organization of matter to higher complexity happens. Because living organisms are machines, the Second Law applies to life as well.

Similarly, it was realized early on that life requires a loss of entropy, or disorder, when molecules organize themselves into living matter. This Second Law of thermodynamics needs to be considered when self-organization of matter to higher complexity happens. Because living organisms are machines, the Second Law applies to life as well.

====Obtaining free energy ====

====Obtaining free energy ====

获得自由能

获得自由能

Bernal said on the Miller–Urey experiment that < blockquote >it is not enough to explain the formation of such molecules, what is necessary, is a physical-chemical explanation of the origins of these molecules that suggests the presence of suitable sources and sinks for free energy.<ref>{{harvnb|Bernal|1967|p=143}}</ref>

Bernal said on the Miller–Urey experiment that < blockquote >it is not enough to explain the formation of such molecules, what is necessary, is a physical-chemical explanation of the origins of these molecules that suggests the presence of suitable sources and sinks for free energy.

< /blockquote >

< /blockquote >

Bernal said on the Miller–Urey experiment that < blockquote >it is not enough to explain the formation of such molecules, what is necessary, is a physical-chemical explanation of the origins of these molecules that suggests the presence of suitable sources and sinks for free energy.< /blockquote >

Bernal said on the Miller–Urey experiment that < blockquote >it is not enough to explain the formation of such molecules, what is necessary, is a physical-chemical explanation of the origins of these molecules that suggests the presence of suitable sources and sinks for free energy.< /blockquote >

伯纳尔Bernal在 Miller-Urey 的实验中说，

伯纳尔Bernal对 Miller-Urey 的实验说到，

< blockquote >仅仅解释这些分子的形成是不够的，需要的是对这些分子的起源作出物理化学解释，表明存在合适的自由能源和自由能汇。

< blockquote >仅仅解释这些分子的形成是不够的，需要的是对这些分子的起源作出物理化学解释，表明存在合适的自由能源和自由能汇。<ref>{{harvnb|Bernal|1967|p=143}}</ref>

</blockquote >

</blockquote >

Multiple sources of energy were available for chemical reactions on the early Earth. For example, heat (such as from [[geothermal energy|geothermal]] processes) is a standard energy source for chemistry. Other examples include sunlight and electrical discharges (lightning), among others.<ref name="Follmann2009" /> In fact, lightning is a plausible energy source for the origin of life, given that just in the tropics lightning strikes about 100 million times a year.<ref>{{Cite journal|last1=Gora|first1=Evan M.|last2=Burchfield|first2=Jeffrey C.|last3=Muller‐Landau|first3=Helene C.|last4=Bitzer|first4=Phillip M.|last5=Yanoviak|first5=Stephen P.|title=Pantropical geography of lightning-caused disturbance and its implications for tropical forests|journal=Global Change Biology|year=2020|language=en|volume=n/a|issue=n/a|pages=5017–5026|doi=10.1111/gcb.15227|pmid=32564481|bibcode=2020GCBio..26.5017G|issn=1365-2486}}</ref>

Multiple sources of energy were available for chemical reactions on the early Earth. For example, heat (such as from [[geothermal energy|geothermal]] processes) is a standard energy source for chemistry. Other examples include sunlight and electrical discharges (lightning), among others.<ref name="Follmann2009" /> In fact, lightning is a plausible energy source for the origin of life, given that just in the tropics lightning strikes about 100 million times a year.

Multiple sources of energy were available for chemical reactions on the early Earth. For example, heat (such as from geothermal processes) is a standard energy source for chemistry. Other examples include sunlight and electrical discharges (lightning), among others. In fact, lightning is a plausible energy source for the origin of life, given that just in the tropics lightning strikes about 100 million times a year.

Multiple sources of energy were available for chemical reactions on the early Earth. For example, heat (such as from geothermal processes) is a standard energy source for chemistry. Other examples include sunlight and electrical discharges (lightning), among others. In fact, lightning is a plausible energy source for the origin of life, given that just in the tropics lightning strikes about 100 million times a year.

Computer simulations also suggest that [[cavitation]] in primordial water reservoirs such as breaking sea waves, streams and oceans can potentially lead to the synthesis of biogenic compounds.<ref>{{cite journal|doi=10.1021/acscentsci.7b00325|pmid= 28979946|pmc= 5620973|title= Cavitation-Induced Synthesis of Biogenic Molecules on Primordial Earth|journal= ACS Central Science|volume= 3|issue= 9|pages= 1041–1049|year= 2017|last1= Kalson|first1= Natan-Haim|last2= Furman|first2= David|last3= Zeiri|first3= Yehuda}}</ref>

Computer simulations also suggest that [[cavitation]] in primordial water reservoirs such as breaking sea waves, streams and oceans can potentially lead to the synthesis of biogenic compounds.

Computer simulations also suggest that cavitation in primordial water reservoirs such as breaking sea waves, streams and oceans can potentially lead to the synthesis of biogenic compounds.

Computer simulations also suggest that cavitation in primordial water reservoirs such as breaking sea waves, streams and oceans can potentially lead to the synthesis of biogenic compounds.

Unfavourable reactions can also be driven by highly favourable ones, as in the case of iron-sulfur chemistry. For example, this was probably important for [[carbon fixation]] (the conversion of carbon from its inorganic form to an organic one). Carbon fixation via iron-sulfur chemistry is highly favourable, and occurs at neutral pH and 100C. Iron-sulfur surfaces, which are abundant near hydrothermal vents, are also capable of producing small amounts of amino acids and other biological metabolites.

Unfavourable reactions can also be driven by highly favourable ones, as in the case of iron-sulfur chemistry. For example, this was probably important for [[carbon fixation]] (the conversion of carbon from its inorganic form to an organic one). Carbon fixation via iron-sulfur chemistry is highly favourable, and occurs at neutral pH and 100C. Iron-sulfur surfaces, which are abundant near hydrothermal vents, are also capable of producing small amounts of amino acids and other biological metabolites.

Unfavourable reactions can also be driven by highly favourable ones, as in the case of iron-sulfur chemistry. For example, this was probably important for carbon fixation (the conversion of carbon from its inorganic form to an organic one). Carbon fixation via iron-sulfur chemistry is highly favourable, and occurs at neutral pH and 100C. Iron-sulfur surfaces, which are abundant near hydrothermal vents, are also capable of producing small amounts of amino acids and other biological metabolites.

Unfavourable reactions can also be driven by highly favourable ones, as in the case of iron-sulfur chemistry. For example, this was probably important for carbon fixation (the conversion of carbon from its inorganic form to an organic one). Carbon fixation via iron-sulfur chemistry is highly favourable, and occurs at neutral pH and 100C. Iron-sulfur surfaces, which are abundant near hydrothermal vents, are also capable of producing small amounts of amino acids and other biological metabolites.

===Self-organization===

===Self-organization===

[[File:Hermann Haken, Pour le Merite 2014.jpg|thumb|upright|Hermann Haken]]

[[File:Hermann Haken, Pour le Merite 2014.jpg|thumb|upright|Hermann Haken]]

赫尔曼•哈肯Hermann Haken

赫尔曼•哈肯Hermann Haken

The discipline of synergetics studies self-organization in physical systems. In his book ''[[Synergetics (Haken)|Synergetics]]''<ref>{{cite book |last1 = Haken| first1= Hermann | title=Synergetics. An Introduction. |year=1978 | publisher=Springer | location= Berlin  }}</ref> [[Hermann Haken]] has pointed out that different physical systems can be treated in a similar way. He gives as examples of self-organization several types of lasers, instabilities in fluid dynamics, including convection, and chemical and biochemical oscillations. In his preface he mentions the origin of life, but only in general terms:

The discipline of synergetics studies self-organization in physical systems. In his book ''[[Synergetics (Haken)|Synergetics]]'' [[Hermann Haken]] has pointed out that different physical systems can be treated in a similar way. He gives as examples of self-organization several types of lasers, instabilities in fluid dynamics, including convection, and chemical and biochemical oscillations. In his preface he mentions the origin of life, but only in general terms:

The discipline of synergetics studies self-organization in physical systems. In his book Synergetics Hermann Haken has pointed out that different physical systems can be treated in a similar way. He gives as examples of self-organization several types of lasers, instabilities in fluid dynamics, including convection, and chemical and biochemical oscillations. In his preface he mentions the origin of life, but only in general terms:

The discipline of synergetics studies self-organization in physical systems. In his book Synergetics Hermann Haken has pointed out that different physical systems can be treated in a similar way. He gives as examples of self-organization several types of lasers, instabilities in fluid dynamics, including convection, and chemical and biochemical oscillations. In his preface he mentions the origin of life, but only in general terms:

协同学这门学科研究的是物理系统的自组织。Hermann Haken在其《协同论》一书中指出，不同的物理系统可以用类似的方式处理。他举了几种类型的激光、流体动力学（包括对流）中的不稳定性以及化学和生化振荡作为自组织的例子。他在序言中提到了生命的起源，但只是泛泛而谈。

协同学这门学科研究的是物理系统的自组织。Hermann Haken在其《协同学》<ref>{{cite book |last1 = Haken| first1= Hermann | title=Synergetics. An Introduction. |year=1978 | publisher=Springer | location= Berlin  }}</ref>一书中指出，不同的物理系统可以用类似的方式处理。他举了几种类型的激光、流体动力学（包括对流）中的不稳定性以及化学和生化振荡作为自组织的例子。他在序言中提到了生命的起源，但只是泛泛而谈。

< blockquote >

< blockquote >

The spontaneous formation of well organized structures out of germs or even out of chaos is one of the most fascinating phenomena and most challenging problems scientists are confronted with. Such phenomena are an experience of our daily life when we observe the growth of plants and animals. Thinking of much larger time scales, scientists are led into the problems of evolution, and, ultimately, of the origin of living matter. When we try to explain or understand in some sense these extremely complex biological phenomena it is a natural question, whether processes of self-organization may be found in much simpler systems of the unanimated world.

The spontaneous formation of well organized structures out of germs or even out of chaos is one of the most fascinating phenomena and most challenging problems scientists are confronted with. Such phenomena are an experience of our daily life when we observe the growth of plants and animals. Thinking of much larger time scales, scientists are led into the problems of evolution, and, ultimately, of the origin of living matter. When we try to explain or understand in some sense these extremely complex biological phenomena it is a natural question, whether processes of self-organization may be found in much simpler systems of the unanimated world.

In recent years it has become more and more evident that there exists numerous examples in physical and chemical systems where well organized spatial, temporal, or spatio-temporal structures arise out of chaotic states. Furthermore, as in living organisms, the functioning of these systems can be maintained only by a flux of energy (and matter) through them. In contrast to man-made machines, which are devised to exhibit special structures and functionings, these structures develop spontaneously—they are selforganizing. ...

In recent years it has become more and more evident that there exists numerous examples in physical and chemical systems where well organized spatial, temporal, or spatio-temporal structures arise out of chaotic states. Furthermore, as in living organisms, the functioning of these systems can be maintained only by a flux of energy (and matter) through them. In contrast to man-made machines, which are devised to exhibit special structures and functionings, these structures develop spontaneously—they are selforganizing. ...

近年来，越来越明显的是，在物理和化学系统中存在着许多例子，在这些例子中，从混沌状态中产生了组织良好的空间、时间或时空结构。此外，就像在生物体中一样，这些系统的功能只能通过能量（和物质）的流动来维持。与人造机器不同的是，人造机器被设计成表现出特殊的结构和功能，这些结构是自发发展的，它们是自组织的...

近年来，越来越明显的是，在物理和化学系统中存在着许多例子，在这些例子中，从混沌状态中产生了组织良好的空间、时间或时空结构。此外，就像在生物体中一样，这些系统的功能只能通过能量（和物质）的流动来维持。与人造机器不同的是，人造机器被设计来表现出特殊的结构和功能，而这些结构是自发发展的，它们是自组织的...

</blockquote >

</blockquote >

多重耗散结构

多重耗散结构

This theory postulates that the hallmark of the origin and evolution of life is the microscopic dissipative structuring of [[Biological pigment|organic pigments]] and their proliferation over the entire Earth surface.<ref name="Michaelian, K. 2017" /> Present day life augments the entropy production of Earth in its solar environment by dissipating [[ultraviolet]] and [[Visible spectrum|visible]] [[photon]]s into heat through organic pigments in water. This heat then catalyzes a host of secondary dissipative processes such as the [[water cycle]], [[Ocean current|ocean]] and [[wind]] currents, [[Tropical cyclone|hurricanes]], etc.<ref name="Michaelian, K. 2011"/><ref name="HESS Opinions 'Biological catalysis">{{cite journal |doi=10.5194/hess-16-2629-2012 |title=HESS Opinions 'Biological catalysis of the hydrological cycle: Life's thermodynamic function' |journal=Hydrology and Earth System Sciences |volume=16 |issue=8 |pages=2629–2645 |year=2012 |last1=Michaelian |first1=K |bibcode=2012HESS...16.2629M |arxiv= 0907.0040 }}</ref>

This theory postulates that the hallmark of the origin and evolution of life is the microscopic dissipative structuring of [[Biological pigment|organic pigments]] and their proliferation over the entire Earth surface. Present day life augments the entropy production of Earth in its solar environment by dissipating [[ultraviolet]] and [[Visible spectrum|visible]] [[photon]]s into heat through organic pigments in water. This heat then catalyzes a host of secondary dissipative processes such as the [[water cycle]], [[Ocean current|ocean]] and [[wind]] currents, [[Tropical cyclone|hurricanes]], etc.

This theory postulates that the hallmark of the origin and evolution of life is the microscopic dissipative structuring of organic pigments and their proliferation over the entire Earth surface. Present day life augments the entropy production of Earth in its solar environment by dissipating ultraviolet and visible photons into heat through organic pigments in water. This heat then catalyzes a host of secondary dissipative processes such as the water cycle, ocean and wind currents, hurricanes, etc.

This theory postulates that the hallmark of the origin and evolution of life is the microscopic dissipative structuring of organic pigments and their proliferation over the entire Earth surface. Present day life augments the entropy production of Earth in its solar environment by dissipating ultraviolet and visible photons into heat through organic pigments in water. This heat then catalyzes a host of secondary dissipative processes such as the water cycle, ocean and wind currents, hurricanes, etc.

==== Selforganization by dissipative structures====

==== Selforganization by dissipative structures====

伊利亚·普里戈金1977c

伊利亚·普里戈金1977c

The 19th-century physicist [[Ludwig Boltzmann]] first recognized that the struggle for existence of living organisms was neither over raw material nor [[energy]], but instead had to do with [[entropy production]] derived from the conversion of the solar [[spectrum]] into [[heat]] by these systems.<ref>Boltzmann, L. (1886) The Second Law of Thermodynamics, in: Ludwig Boltzmann: Theoretical physics and Selected writings, edited by: McGinness, B., D. Reidel, Dordrecht, The Netherlands, 1974.</ref> Boltzmann thus realized that living systems, like all [[Reversible process (thermodynamics)|irreversible processes]], were dependent on the [[dissipation]] of a generalized chemical potential for their existence. In his book "What is Life", the 20th-century physicist [[Erwin Schrödinger]]<ref>Schrödinger, Erwin (1944) What is Life? The Physical Aspect of the Living Cell. Cambridge University Press</ref> emphasized the importance of Boltzmann's deep insight into the irreversible thermodynamic nature of living systems, suggesting that this was the physics and chemistry behind the origin and evolution of life.

The 19th-century physicist [[Ludwig Boltzmann]] first recognized that the struggle for existence of living organisms was neither over raw material nor [[energy]], but instead had to do with [[entropy production]] derived from the conversion of the solar [[spectrum]] into [[heat]] by these systems. Boltzmann thus realized that living systems, like all [[Reversible process (thermodynamics)|irreversible processes]], were dependent on the [[dissipation]] of a generalized chemical potential for their existence. In his book "What is Life", the 20th-century physicist [[Erwin Schrödinger]] emphasized the importance of Boltzmann's deep insight into the irreversible thermodynamic nature of living systems, suggesting that this was the physics and chemistry behind the origin and evolution of life.

The 19th-century physicist Ludwig Boltzmann first recognized that the struggle for existence of living organisms was neither over raw material nor energy, but instead had to do with entropy production derived from the conversion of the solar spectrum into heat by these systems. Boltzmann thus realized that living systems, like all irreversible processes, were dependent on the dissipation of a generalized chemical potential for their existence. In his book "What is Life", the 20th-century physicist Erwin Schrödinger emphasized the importance of Boltzmann's deep insight into the irreversible thermodynamic nature of living systems, suggesting that this was the physics and chemistry behind the origin and evolution of life.

The 19th-century physicist Ludwig Boltzmann first recognized that the struggle for existence of living organisms was neither over raw material nor energy, but instead had to do with entropy production derived from the conversion of the solar spectrum into heat by these systems. Boltzmann thus realized that living systems, like all irreversible processes, were dependent on the dissipation of a generalized chemical potential for their existence. In his book "What is Life", the 20th-century physicist Erwin Schrödinger emphasized the importance of Boltzmann's deep insight into the irreversible thermodynamic nature of living systems, suggesting that this was the physics and chemistry behind the origin and evolution of life.

19世纪的物理学家路德维希-玻尔兹曼Ludwig Boltzmann首先认识到，生物体的生存斗争既不是为了原料，也不是为了能源，而是与这些系统将太阳光谱转化为热能所产生的熵有关，Boltzmann由此认识到，生物系统和所有不可逆的过程一样，其存在依赖于广义化学势的消散。20世纪物理学家Erwin Schrödinger在其《生命是什么》一书中强调了Boltzmann对生命系统不可逆的热力学本质的深刻洞察，认为这就是生命起源和进化背后的物理学和化学。

19世纪的物理学家路德维希-玻尔兹曼Ludwig Boltzmann首先认识到，生物体的生存斗争既不是为了原料，也不是为了能源，而是与这些系统将太阳光谱转化为热能所带来的熵增有关。<ref>Boltzmann, L. (1886) The Second Law of Thermodynamics, in: Ludwig Boltzmann: Theoretical physics and Selected writings, edited by: McGinness, B., D. Reidel, Dordrecht, The Netherlands, 1974.</ref>Boltzmann由此认识到，生物系统和所有不可逆的过程一样，其存在依赖于广义化学势的消散。20世纪物理学家Erwin Schrödinger在其《生命是什么》一书中<ref>Schrödinger, Erwin (1944) What is Life? The Physical Aspect of the Living Cell. Cambridge University Press</ref>强调了Boltzmann对生命系统不可逆的热力学本质的深刻洞察，认为这就是生命起源和演化背后的物理学和化学。

However, irreversible processes, and much less living systems, could not be conveniently analyzed under this perspective until [[Lars Onsager]],<ref>Onsager, L. (1931) Reciprocal Relations in Irreversible Processes I and II, ''Phys. Rev.'' 37, 405; 38, 2265 (1931)</ref> and later Ilya [[Ilya Prigogine|Prigogine]],<ref>Prigogine, I. (1967) An Introduction to the Thermodynamics of Irreversible Processes, Wiley, New York</ref> developed an elegant mathematical formalism for treating the "self-organization" of material under a generalized chemical potential. This formalism became known as Classical Irreversible Thermodynamics and Prigogine was awarded the [[Nobel Prize in Chemistry]] in 1977 "for his contributions to [[non-equilibrium thermodynamics]], particularly the theory of [[Dissipative system|dissipative structures]]". The analysis by Prigogine showed that if a [[system]] were left to evolve under an imposed external potential, material could spontaneously organize (lower its [[entropy]]) forming what he called "dissipative structures" which would increase the dissipation of the externally imposed potential (augment the global entropy production). Non-equilibrium thermodynamics has since been successfully applied to the analysis of living systems, from the biochemical production of [[Adenosine triphosphate|ATP]]<ref>{{cite journal | last1 = Dewar | first1 = R | last2 = Juretić | first2 = D. | last3 = Županović | first3 = P. | year = 2006 | title = The functional design of the rotary enzyme ATP synthase is consistent with maximum entropy production | journal = Chem. Phys. Lett. | volume = 430 | issue = 1| pages = 177–182 | doi=10.1016/j.cplett.2006.08.095| bibcode = 2006CPL...430..177D }}</ref> to optimizing bacterial metabolic pathways<ref>Unrean, P., Srienc, F. (2011) Metabolic networks evolve towards states of maximum entropy production, Metabolic Engineering 13, 666–673.</ref> to complete ecosystems.<ref>Zotin, A.I. (1984) "Bioenergetic trends of evolutionary progress of organisms", in: ''Thermodynamics and regulation of biological processes'' Lamprecht, I. and Zotin, A.I. (eds.), De Gruyter, Berlin, pp. 451–458.</ref><ref>{{cite journal | last1 = Schneider | first1 = E.D. | last2 = Kay | first2 = J.J. | year = 1994 | title = Life as a Manifestation of the Second Law of Thermodynamics | journal = Mathematical and Computer Modelling | volume = 19 | issue = 6–8| pages = 25–48 | doi=10.1016/0895-7177(94)90188-0| citeseerx = 10.1.1.36.8381 }}</ref><ref>{{cite journal | last1 = Michaelian | first1 = K. | year = 2005 | title = Thermodynamic stability of ecosystems  | journal = Journal of Theoretical Biology | volume = 237 | issue = 3| pages = 323–335 | bibcode = 2004APS..MAR.P9015M | doi=10.1016/j.jtbi.2005.04.019| pmid = 15978624 }}</ref>

However, irreversible processes, and much less living systems, could not be conveniently analyzed under this perspective until [[Lars Onsager]], and later Ilya [[Ilya Prigogine|Prigogine]], developed an elegant mathematical formalism for treating the "self-organization" of material under a generalized chemical potential. This formalism became known as Classical Irreversible Thermodynamics and Prigogine was awarded the [[Nobel Prize in Chemistry]] in 1977 "for his contributions to [[non-equilibrium thermodynamics]], particularly the theory of [[Dissipative system|dissipative structures]]". The analysis by Prigogine showed that if a [[system]] were left to evolve under an imposed external potential, material could spontaneously organize (lower its [[entropy]]) forming what he called "dissipative structures" which would increase the dissipation of the externally imposed potential (augment the global entropy production). Non-equilibrium thermodynamics has since been successfully applied to the analysis of living systems, from the biochemical production of [[Adenosine triphosphate|ATP]] to optimizing bacterial metabolic pathways to complete ecosystems.

However, irreversible processes, and much less living systems, could not be conveniently analyzed under this perspective until Lars Onsager, and later Ilya Prigogine, developed an elegant mathematical formalism for treating the "self-organization" of material under a generalized chemical potential. This formalism became known as Classical Irreversible Thermodynamics and Prigogine was awarded the Nobel Prize in Chemistry in 1977 "for his contributions to non-equilibrium thermodynamics, particularly the theory of dissipative structures". The analysis by Prigogine showed that if a system were left to evolve under an imposed external potential, material could spontaneously organize (lower its entropy) forming what he called "dissipative structures" which would increase the dissipation of the externally imposed potential (augment the global entropy production). Non-equilibrium thermodynamics has since been successfully applied to the analysis of living systems, from the biochemical production of ATP to optimizing bacterial metabolic pathways to complete ecosystems.

However, irreversible processes, and much less living systems, could not be conveniently analyzed under this perspective until Lars Onsager, and later Ilya Prigogine, developed an elegant mathematical formalism for treating the "self-organization" of material under a generalized chemical potential. This formalism became known as Classical Irreversible Thermodynamics and Prigogine was awarded the Nobel Prize in Chemistry in 1977 "for his contributions to non-equilibrium thermodynamics, particularly the theory of dissipative structures". The analysis by Prigogine showed that if a system were left to evolve under an imposed external potential, material could spontaneously organize (lower its entropy) forming what he called "dissipative structures" which would increase the dissipation of the externally imposed potential (augment the global entropy production). Non-equilibrium thermodynamics has since been successfully applied to the analysis of living systems, from the biochemical production of ATP to optimizing bacterial metabolic pathways to complete ecosystems.

然而，不可逆的过程，更不用说生命系统了，在这个角度下无法方便地进行分析，直到Lars Onsager和后来的Ilya Prigogine，发展了一种优雅的数学形式论，用于处理广义化学势下物质的 "自组织"。这个形式论后来被称为经典不可逆热力学，1977年Prigogine被授予诺贝尔化学奖，"以表彰他对非平衡热力学，特别是耗散结构理论的贡献"。Prigogine的分析表明，如果让一个系统在一个强加的外部势下演化，物质可以自发地组织起来（降低其熵），形成他所说的 "耗散结构"，从而增加外部强加势的耗散（增强全局熵的产生）。此后，非平衡热力学被成功地应用于生命系统的分析，从ATP的生化生产到优化细菌代谢途径，再到完整的生态系统。

然而，不可逆的过程，更不用说生命系统，直到Lars Onsager<ref>Onsager, L. (1931) Reciprocal Relations in Irreversible Processes I and II, ''Phys. Rev.'' 37, 405; 38, 2265 (1931)</ref>和后来的Ilya Prigogine<ref>Prigogine, I. (1967) An Introduction to the Thermodynamics of Irreversible Processes, Wiley, New York</ref>发展了一种优雅的数学形式论，才能在这个角度下方便地进行分析。这个形式论用于处理广义化学势下物质的 "自组织"，这个形式论后来被称为经典不可逆热力学，1977年Prigogine被授予诺贝尔化学奖，"以表彰他对非平衡热力学，特别是耗散结构理论的贡献"。Prigogine的分析表明，如果让一个系统在一个强加的外部势下演化，物质可以自发地组织起来（降低其熵），形成他所说的 "耗散结构"，从而增加外部强加势的耗散（增强全局熵的产生）。此后，非平衡热力学被成功地应用于生命系统的分析，从ATP的生化生产<ref>{{cite journal | last1 = Dewar | first1 = R | last2 = Juretić | first2 = D. | last3 = Županović | first3 = P. | year = 2006 | title = The functional design of the rotary enzyme ATP synthase is consistent with maximum entropy production | journal = Chem. Phys. Lett. | volume = 430 | issue = 1| pages = 177–182 | doi=10.1016/j.cplett.2006.08.095| bibcode = 2006CPL...430..177D }}</ref>到优化细菌代谢途径<ref>Unrean, P., Srienc, F. (2011) Metabolic networks evolve towards states of maximum entropy production, Metabolic Engineering 13, 666–673.</ref>，再到完整的生态系统。<ref>Zotin, A.I. (1984) "Bioenergetic trends of evolutionary progress of organisms", in: ''Thermodynamics and regulation of biological processes'' Lamprecht, I. and Zotin, A.I. (eds.), De Gruyter, Berlin, pp. 451–458.</ref><ref>{{cite journal | last1 = Schneider | first1 = E.D. | last2 = Kay | first2 = J.J. | year = 1994 | title = Life as a Manifestation of the Second Law of Thermodynamics | journal = Mathematical and Computer Modelling | volume = 19 | issue = 6–8| pages = 25–48 | doi=10.1016/0895-7177(94)90188-0| citeseerx = 10.1.1.36.8381 }}</ref><ref>{{cite journal | last1 = Michaelian | first1 = K. | year = 2005 | title = Thermodynamic stability of ecosystems  | journal = Journal of Theoretical Biology | volume = 237 | issue = 3| pages = 323–335 | bibcode = 2004APS..MAR.P9015M | doi=10.1016/j.jtbi.2005.04.019| pmid = 15978624 }}</ref>

==当前的生命，生物发生的结果：生物学 Current life, the result of abiogenesis: biology==

==当前的生命，生物发生的结果：生物学 Current life, the result of abiogenesis: biology==