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'''前额叶皮质基底节工作记忆记忆模型 Prefrontal Cortex Basal Ganglia Working Memory (PBWM)'''是模拟神经生理学和工作记忆功能模型的一种。

'''前额叶皮质基底节工作记忆记忆模型 Prefrontal Cortex Basal Ganglia Working Memory (PBWM)'''是模拟神经生理学和工作记忆功能模型的一种。

在该模型中，脑前额叶外皮与基底神经节协力完成工作记忆任务，并得到许多研究证明支持<ref>{{Cite journal|last1=Baier|first1=B.|last2=Karnath|first2=H.-O.|last3=Dieterich|first3=M.|last4=Birklein|first4=F.|last5=Heinze|first5=C.|last6=Muller|first6=N. G.|date=2010-07-21|title=Keeping Memory Clear and Stable--The Contribution of Human Basal Ganglia and Prefrontal Cortex to Working Memory|journal=Journal of Neuroscience|volume=30|issue=29|pages=9788–9792|doi=10.1523/jneurosci.1513-10.2010|pmid=20660261|pmc=6632833|issn=0270-6474|doi-access=free}}</ref>，例如使用'''消融技术ablation techniques'''治疗脑前额叶外皮和基底神经节受损、癫痫发作患者等。<ref name=":2" />研究人员发现，这种损害使得工作记忆的执行功能受损。<ref name=":2">{{Cite journal|last1=Voytek|first1=B.|last2=Knight|first2=R. T.|date=2010-10-04|title=Prefrontal cortex and basal ganglia contributions to visual working memory|journal=Proceedings of the National Academy of Sciences|volume=107|issue=42|pages=18167–18172|doi=10.1073/pnas.1007277107|pmid=20921401|issn=0027-8424|doi-access=free}}</ref>此外还有对因服用'''甲基苯丙胺 methamphetamine'''而导致大脑改变的病人进行工作记忆训练后成功增加其基底神经节容量的案例<ref>{{Cite journal|last1=Brooks|first1=S. J.|last2=Burch|first2=K. H.|last3=Maiorana|first3=S. A.|last4=Cocolas|first4=E.|last5=Schioth|first5=H. B.|last6=Nilsson|first6=E. K.|last7=Kamaloodien|first7=K.|last8=Stein|first8=D. J.|date=2016-02-01|title=Psychological intervention with working memory training increases basal ganglia volume: A VBM study of inpatient treatment for methamphetamine use|url=http://www.sciencedirect.com/science/article/pii/S2213158216301541|journal=NeuroImage: Clinical|language=en|volume=12|pages=478–491|doi=10.1016/j.nicl.2016.08.019|pmid=27625988|issn=2213-1582|doi-access=free}}</ref>。

在该模型中，脑前额叶外皮与基底神经节协力完成工作记忆任务，并得到许多研究证明支持<ref>{{Cite journal|last1=Baier|first1=B.|last2=Karnath|first2=H.-O.|last3=Dieterich|first3=M.|last4=Birklein|first4=F.|last5=Heinze|first5=C.|last6=Muller|first6=N. G.|date=2010-07-21|title=Keeping Memory Clear and Stable--The Contribution of Human Basal Ganglia and Prefrontal Cortex to Working Memory|journal=Journal of Neuroscience|volume=30|issue=29|pages=9788–9792|doi=10.1523/jneurosci.1513-10.2010|pmid=20660261|pmc=6632833|issn=0270-6474|doi-access=free}}</ref>，例如使用'''消融技术 ablation techniques'''治疗脑前额叶外皮和基底神经节受损、癫痫发作患者等。<ref name=":2" />研究人员发现，这种损害使得工作记忆的执行功能受损。<ref name=":2">{{Cite journal|last1=Voytek|first1=B.|last2=Knight|first2=R. T.|date=2010-10-04|title=Prefrontal cortex and basal ganglia contributions to visual working memory|journal=Proceedings of the National Academy of Sciences|volume=107|issue=42|pages=18167–18172|doi=10.1073/pnas.1007277107|pmid=20921401|issn=0027-8424|doi-access=free}}</ref>此外还有对因服用'''甲基苯丙胺 methamphetamine'''而导致大脑改变的病人进行工作记忆训练后成功增加其基底神经节容量的案例<ref>{{Cite journal|last1=Brooks|first1=S. J.|last2=Burch|first2=K. H.|last3=Maiorana|first3=S. A.|last4=Cocolas|first4=E.|last5=Schioth|first5=H. B.|last6=Nilsson|first6=E. K.|last7=Kamaloodien|first7=K.|last8=Stein|first8=D. J.|date=2016-02-01|title=Psychological intervention with working memory training increases basal ganglia volume: A VBM study of inpatient treatment for methamphetamine use|url=http://www.sciencedirect.com/science/article/pii/S2213158216301541|journal=NeuroImage: Clinical|language=en|volume=12|pages=478–491|doi=10.1016/j.nicl.2016.08.019|pmid=27625988|issn=2213-1582|doi-access=free}}</ref>。

=== 神经生理学的压力效果 ===

=== 神经生理学的压力效果 ===