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thumb|right|350px|Basic components of Hodgkin–Huxley-type models. Hodgkin–Huxley type models represent the biophysical characteristic of cell membranes. The lipid bilayer is represented as a capacitance (C<SUB>m</SUB>). Voltage-gated and leak ion channels are represented by nonlinear (g<SUB>n</SUB>) and linear (g<SUB>L</SUB>) conductances, respectively. The electrochemical gradients driving the flow of ions are represented by batteries (E), and ion pumps and exchangers are represented by current sources (I<SUB>p</SUB>).

thumb|right|350px|Basic components of Hodgkin–Huxley-type models. Hodgkin–Huxley type models represent the biophysical characteristic of cell membranes. The lipid bilayer is represented as a capacitance (C<SUB>m</SUB>). Voltage-gated and leak ion channels are represented by nonlinear (g<SUB>n</SUB>) and linear (g<SUB>L</SUB>) conductances, respectively. The electrochemical gradients driving the flow of ions are represented by batteries (E), and ion pumps and exchangers are represented by current sources (I<SUB>p</SUB>).

Hodgkin-Huxley 型模型的基本组成部分。Hodgkin-Huxley 型模型代表了细胞膜的生物物理特性。磷脂双分子层表示为一个电容项。电压门控离子通道和漏离子通道分别用非线性和线性电导表示。驱动离子流动的电化学梯度用电池(e)表示，离子泵和离子交换器用电流源表示(i < sub > p )。

Hodgkin-Huxley 型模型的基本组成部分。Hodgkin-Huxley 型模型代表了细胞膜的生物物理特性。磷脂双分子层表示为一个电容项(''C<SUB>m</SUB>'')。电压门控离子通道和漏离子通道分别用非线性(''g<SUB>n</SUB>'')和线性电导(''g<SUB>L</SUB>'')表示。驱动离子流动的电化学梯度用电池(''E'')表示，离子泵和离子交换器用电流源表示(''I<SUB>p</SUB>'')。

The '''Hodgkin–Huxley model''', or '''conductance-based model''', is a [[mathematical model]] that describes how [[action potential]]s in [[neuron]]s are initiated and propagated. It is a set of [[nonlinear]] [[differential equation]]s that approximates the electrical characteristics of excitable cells such as neurons and [[cardiac muscle|cardiac myocytes]]. It is a continuous-time [[dynamical system]].

The '''Hodgkin–Huxley model''', or '''conductance-based model''', is a [[mathematical model]] that describes how [[action potential]]s in [[neuron]]s are initiated and propagated. It is a set of [[nonlinear]] [[differential equation]]s that approximates the electrical characteristics of excitable cells such as neurons and [[cardiac muscle|cardiac myocytes]]. It is a continuous-time [[dynamical system]].

[[Alan Hodgkin]] and [[Andrew Huxley]] described the model in 1952 to explain the ionic mechanisms underlying the initiation and propagation of action potentials in the [[squid giant axon]].<ref name=HH>{{cite journal | vauthors = Hodgkin AL, Huxley AF | title = A quantitative description of membrane current and its application to conduction and excitation in nerve | journal = The Journal of Physiology | volume = 117 | issue = 4 | pages = 500–44 | date = August 1952 | pmid = 12991237 | pmc = 1392413 | doi = 10.1113/jphysiol.1952.sp004764 }}</ref>  They received the 1963 [[Nobel Prize in Physiology or Medicine]] for this work.

[[Alan Hodgkin]] and [[Andrew Huxley]] described the model in 1952 to explain the ionic mechanisms underlying the initiation and propagation of action potentials in the [[squid giant axon]].<ref name=HH>{{cite journal | vauthors = Hodgkin AL, Huxley AF | title = A quantitative description of membrane current and its application to conduction and excitation in nerve | journal = The Journal of Physiology | volume = 117 | issue = 4 | pages = 500–44 | date = August 1952 | pmid = 12991237 | pmc = 1392413 | doi = 10.1113/jphysiol.1952.sp004764 }}</ref>  They received the 1963 [[Nobel Prize in Physiology or Medicine]] for this work.

1952年，Alan Hodgkin 和 Andrew Huxley 描述了这个模型，来解释乌贼巨大神经轴突中动作电位的产生和传导的离子机制。他们因为这项工作获得了1963年的诺贝尔生理学或医学奖。

1952年，Alan Hodgkin 和 Andrew Huxley 描述了这个模型，来解释乌贼巨大轴突中动作电位的产生和传导的离子机制。<ref name="HH" />他们因为这项工作获得了1963年的诺贝尔生理学或医学奖。

==基本成分==

==基本成分==