One approach to modeling the neurophysiology and the functioning of working memory is prefrontal cortex basal ganglia working memory (PBWM). In this model, the prefrontal cortex works hand-in-hand with the basal ganglia to accomplish the tasks of working memory. Many studies have shown this to be the case. One used ablation techniques in patients who had suffered from seizures and had damage to the prefrontal cortex and basal ganglia. Additional research conducted on patients with brain alterations due to methamphetamine use found that training working memory increases volume in the basal ganglia. | One approach to modeling the neurophysiology and the functioning of working memory is prefrontal cortex basal ganglia working memory (PBWM). In this model, the prefrontal cortex works hand-in-hand with the basal ganglia to accomplish the tasks of working memory. Many studies have shown this to be the case. One used ablation techniques in patients who had suffered from seizures and had damage to the prefrontal cortex and basal ganglia. Additional research conducted on patients with brain alterations due to methamphetamine use found that training working memory increases volume in the basal ganglia. |